STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PH1078450aa long hypothetical fmu protein; Similar to PIR:B64303 percent identity: 36.150 in 222aa; PIR:S74920 percent identity: 28.375 in 373aa; owl:A48998 percent identity: 32.660 in 313aa; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (450 aa)    
Predicted Functional Partners:
PH0281
174aa long hypothetical protein; Belongs to the UPF0113 family.
  
 
 0.738
PH1320
357aa long hypothetical protein; Similar to PIR:G64475 percent identity: 53.395 in 332aa; owl:S61973 percent identity: 31.615 in 291aa. motif=ATP/GTP-binding site motif A (P-loop).
   
 
 0.730
PH0645
355aa long hypothetical GTP-binding protein; Similar to PIR:G64482 percent identity: 43.825 in 251aa; owl:HUMAUANTIG percent identity: 36.145 in 261aa; owl:MMU69600 percent identity: 36.000 in 262aa. motif=ATP/GTP-binding site motif A (P-loop).
  
 
 0.724
PH1079
221aa long hypothetical protein; Motif=prokaryotic membrane lipoprotein lipid attachment site.
       0.693
PH1947
1235aa long hypothetical DNA-directed DNA polymerase; Similar to PIR:S68593 percent identity: 75.831 in 1312aa; Swiss_Prot:P30317 percent identity: 67.133 in 1082aa; owl:PYWKODPOL percent identity: 75.792 in 1671aa. motif=DNA polymerase family B signature; protein splicing signature; Belongs to the DNA polymerase type-B family.
  
  
 0.679
PH0053
404aa long hypothetical protein; Similar to PIR:F64386 percent identity: 52.669 in 283aa; owl:CEK07C53 percent identity: 39.249 in 306aa; owl:HSNOP56 percent identity: 41.102 in 239aa.
   
 
 0.678
PH1076
303aa long hypothetical protein.
       0.658
PH1103
127aa long hypothetical 30S ribosomal protein S8; Similar to Swiss_Prot:P54055 percent identity: 62.992 in 129aa; Swiss_Prot:P49402 percent identity: 49.167 in 122aa.
   
 
 0.658
PH1999
342aa long hypothetical acidic ribosomal protein P0 (L10E); Forms the large subunit's ribosomal stalk, playing a central role in the interaction of the ribosome with elongation factors; the stalk complex of P.horikoshii binds to E.coli large subunits and confers on them the ability to interact with eukaryotic elongation factors. Each succesive L12 dimer bound along the P0 spine increases the GTPase activity of elongation factors and increases translation by reconsituted ribosomes, although the first site is the most stimulatory; Belongs to the universal ribosomal protein uL10 family.
  
 
 0.632
PH1900
334aa long hypothetical protein; Probably involved in the biogenesis of the ribosome.
   
 
 0.627
Your Current Organism:
Pyrococcus horikoshii
NCBI taxonomy Id: 70601
Other names: P. horikoshii OT3, Pyrococcus horikoshii OT-3, Pyrococcus horikoshii OT3, Pyrococcus horikoshii str. OT3, Pyrococcus shinkaii OT3, Pyrococcus sp. OT3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.