STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PH1202371aa long hypothetical protein; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (371 aa)    
Predicted Functional Partners:
PH1072
342aa long hypothetical geranylgeranyl pyrophosphate synthetase; Similar to owl:S75695B percent identity: 49.226 in 337aa; PIR:D64407 percent identity: 52.218 in 309aa; owl:SS56KBFR60 percent identity: 44.610 in 272aa. motif=polyprenyl synthetases signatures; Belongs to the FPP/GGPP synthase family.
  
 
 0.965
PH1623
254aa long hypothetical protein; Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids.
 
  
  0.942
PH1625
335aa long hypothetical mevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
 
  
 0.795
PH0999
180aa long hypothetical pyrazinamidase/nicotinamidase; Similar to owl:AF0082061 percent identity: 39.884 in 183aa; owl:MTU59967 percent identity: 39.306 in 182aa; Swiss_Prot:P21369 percent identity: 41.954 in 199aa.
     
 0.743
PHS037
51aa long hypothetical 50S ribosomal protein L40; Similar to Swiss_Prot:P54058 percent identity: 71.111 in 45aa; Belongs to the eukaryotic ribosomal protein eL40 family.
   
 
 0.658
PH0677
350aa long hypothetical acyl carrier protein synthetase; Similar to owl:PFPORVOR4 percent identity: 90.857 in 350aa; PIR:A64493 percent identity: 63.772 in 342aa; owl:PFU418184 percent identity: 38.507 in 351aa; Belongs to the thiolase-like superfamily. UPF0219 family.
 
  
 0.635
PH1308
386aa long hypothetical serine aminotransferase; Similar to PIR:G64419 percent identity: 34.637 in 362aa; PIR:JC2256 percent identity: 33.803 in 360aa; owl:S75916 percent identity: 34.551 in 364aa.
  
 
 0.591
PH1805
341aa long hypothetical 3-hydroxy-3-methylglutaryl coenzyme A reductase; Converts HMG-CoA to mevalonate.
 
   
 0.588
PH1629
205aa long hypothetical 30S ribosomal protein S2; Similar to Swiss_Prot:P54109 percent identity: 66.667 in 192aa; owl:SS56KBFR54 percent identity: 57.071 in 198aa; Swiss_Prot:P29202 percent identity: 57.627 in 177aa. motif=ribosomal protein S2 signatures; Belongs to the universal ribosomal protein uS2 family.
  
  
 0.561
PH1204
187aa long hypothetical protein.
       0.550
Your Current Organism:
Pyrococcus horikoshii
NCBI taxonomy Id: 70601
Other names: P. horikoshii OT3, Pyrococcus horikoshii OT-3, Pyrococcus horikoshii OT3, Pyrococcus horikoshii str. OT3, Pyrococcus shinkaii OT3, Pyrococcus sp. OT3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.