STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PH1265192aa long hypothetical cytidylate kinase; Similar to PIR:H64381 percent identity: 61.628 in 176aa; owl:SARL34CDK2 percent identity: 43.713 in 169aa. (192 aa)    
Predicted Functional Partners:
PHS035
94aa long hypothetical 50S ribosomal protein L34; Similar to Swiss_Prot:P54053 percent identity: 63.095 in 85aa; GENPEPT:Y13049 percent identity: 43.750 in 84aa; Swiss_Prot:P45842 percent identity: 36.986 in 74aa; Belongs to the eukaryotic ribosomal protein eL34 family.
 
    0.976
PH1644
334aa long hypothetical centromere/microtubule binding protein; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
      0.928
PH0698
160aa long hypothetical nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
     
 0.921
PH0363
1291aa long hypothetical ribonucleoside-diphosphate reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
    
  0.904
PH1589
182aa long hypothetical deoxycytidylate deaminase; Similar to Swiss_Prot:P32393 percent identity: 48.673 in 113aa. motif=cytidine and deoxycytidylate deaminases zinc-binding region signature.
     
  0.900
PH1776
255aa long hypothetical 50S ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
  
    0.877
PH1773
155aa long hypothetical 50S ribosomal protein L22; This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
  
    0.875
PH1766
243aa long hypothetical 30S ribosomal protein S4; Similar to Swiss_Prot:P54039 percent identity: 52.720 in 247aa; Swiss_Prot:P14023 percent identity: 47.280 in 247aa; GENPEPT:Y07778 percent identity: 36.752 in 238aa. motif=ribosomal protein S4e signature; Belongs to the eukaryotic ribosomal protein eS4 family.
  
    0.873
PH1767
124aa long hypothetical 50S ribosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
  
    0.873
PH1768
144aa long hypothetical 50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
  
    0.873
Your Current Organism:
Pyrococcus horikoshii
NCBI taxonomy Id: 70601
Other names: P. horikoshii OT3, Pyrococcus horikoshii OT-3, Pyrococcus horikoshii OT3, Pyrococcus horikoshii str. OT3, Pyrococcus shinkaii OT3, Pyrococcus sp. OT3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.