STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PH1267335aa long hypothetical protein; Similar to PIR:G64366 percent identity: 49.669 in 303aa; PIR:S74557 percent identity: 37.751 in 265aa. (335 aa)    
Predicted Functional Partners:
PH0900
902aa long hypothetical protein.
   
 0.841
PH0947
249aa long hypothetical protein; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription. Belongs to the sirtuin family. Class III subfamily.
   
 
 0.762
PH1804
441aa long hypothetical protein; Similar to owl:AB002406 percent identity: 49.883 in 443aa; PIR:S52698 percent identity: 48.219 in 435aa; PIR:S61029 percent identity: 45.564 in 431aa. motif=ATP/GTP-binding site motif A (P-loop).
  
 
 0.749
PH0687
840aa long hypothetical cell division control protein (transitional endoplasmic reticulum ATPase); Similar to PIR:C64444 percent identity: 68.554 in 760aa; Swiss_Prot:Q07590 percent identity: 62.391 in 771aa; owl:TAU78072 percent identity: 61.891 in 761aa. motif=AAA-protein family signature; ATP/GTP-binding site motif A (P-loop).
   
 0.684
PH1278
363aa long hypothetical protein; Similar to Swiss_Prot:P52917 percent identity: 45.778 in 232aa; Swiss_Prot:Q09803 percent identity: 42.478 in 233aa; Swiss_Prot:P46467 percent identity: 43.556 in 233aa. motif=ATP/GTP-binding site motif A (P-loop).
   
 0.684
PH1840
798aa long hypothetical transitional endoplasmic reticulum ATPase; Similar to PIR:C64444 percent identity: 70.579 in 736aa; Swiss_Prot:Q07590 percent identity: 62.185 in 778aa; owl:TAU78072 percent identity: 59.097 in 799aa. motif=AAA-protein family signature; ATP/GTP-binding site motif A (P-loop).
   
 0.684
PH0965
967aa long hypothetical leucyl-tRNA synthetase; Similar to PIR:A64379 percent identity: 53.987 in 980aa; owl:F21M12 percent identity: 36.017 in 737aa; Swiss_Prot:Q09996 percent identity: 34.910 in 766aa. motif=aminoacyl-transfer RNA synthetases class-I signature.
  
 
 
 0.660
PH1009
191aa long hypothetical TATA-binding protein (transcription initiation factor TFIID); General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation (By similarity).
 
 0.614
PH1704
166aa long hypothetical intracellular proteinase; Deglycase that catalyzes the deglycation of the Maillard adducts formed between amino groups of proteins and reactive carbonyl groups of glyoxals. Thus, functions as a protein deglycase that repairs methylglyoxal- and glyoxal-glycated proteins, and releases repaired proteins and lactate or glycolate, respectively. Deglycates cysteine, arginine and lysine residues in proteins, and thus reactivates these proteins by reversing glycation by glyoxals. Acts on early glycation intermediates (hemithioacetals and aminocarbinols), preventing the [...]
  
 0.607
PHS037
51aa long hypothetical 50S ribosomal protein L40; Similar to Swiss_Prot:P54058 percent identity: 71.111 in 45aa; Belongs to the eukaryotic ribosomal protein eL40 family.
    
  0.593
Your Current Organism:
Pyrococcus horikoshii
NCBI taxonomy Id: 70601
Other names: P. horikoshii OT3, Pyrococcus horikoshii OT-3, Pyrococcus horikoshii OT3, Pyrococcus horikoshii str. OT3, Pyrococcus shinkaii OT3, Pyrococcus sp. OT3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.