STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PH1812424aa long hypothetical protein; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. (424 aa)    
Predicted Functional Partners:
PH0285
112aa long hypothetical methionyl-tRNA synthetase; Similar to PIR:F64457 percent identity:45.370 in 108aa; Swiss_Prot:P23395 percent identity:48.485 in 100aa.
      
 0.769
PH1818
398aa long hypothetical protein.
 
     0.711
PH1815
284aa long hypothetical cobalt transport ATP-binding protein; Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system (By similarity).
       0.680
PH1813
496aa long hypothetical TRK system potassium uptake protein; Similar to PIR:D64485 percent identity: 37.556 in 468aa; Swiss_Prot:P23849 percent identity: 28.879 in 476aa; Swiss_Prot:P44843 percent identity: 33.226 in 321aa. motif=prokaryotic membrane lipoprotein lipid attachment site.
       0.667
PH0461
206aa long hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs. Belongs to the aTrm56 family.
  
     0.661
PH1816
329aa long hypothetical protein.
       0.661
PH0660
212aa long hypothetical protein; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family.
  
     0.623
PH1909
179aa long hypothetical protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
 
     0.618
PH1105
342aa long hypothetical protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2).
 
     0.583
PH1811
159aa long hypothetical molybdenum cofactor biosynthesis protein; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
       0.569
Your Current Organism:
Pyrococcus horikoshii
NCBI taxonomy Id: 70601
Other names: P. horikoshii OT3, Pyrococcus horikoshii OT-3, Pyrococcus horikoshii OT3, Pyrococcus horikoshii str. OT3, Pyrococcus shinkaii OT3, Pyrococcus sp. OT3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.