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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PH0056230aa long hypothetical HESA protein; Similar to Swiss_Prot:P46048 percent identity: 44.037 in 223aa; Swiss_Prot:P18500 percent identity: 41.872 in 206aa; PIR:A49890 percent identity: 39.450 in 223aa. (230 aa)    
Predicted Functional Partners:
PH0184
149aa long hypothetical molybdopterinconverting factor, subunit; Similar to owl:MTCY16429 percent identity: 38.525 in 122aa; owl:ATAC00233312 percent identity: 34.752 in 141aa; Swiss_Prot:P30749 percent identity: 40.171 in 117aa. motif=tonB-dependent receptor proteins signatures.
 
 0.995
PHS037
51aa long hypothetical 50S ribosomal protein L40; Similar to Swiss_Prot:P54058 percent identity: 71.111 in 45aa; Belongs to the eukaryotic ribosomal protein eL40 family.
   
 0.944
PH1156
161aa long hypothetical thiamine biosynthetic bifunctional protein; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
  
 0.865
PH1155
446aa long hypothetical thiamine biosynthesis protein; Similar to Swiss_Prot:P44697 percent identity: 51.538 in 267aa; owl:HPAE0005959 percent identity: 44.531 in 262aa; owl:MTCY22G1018 percent identity: 44.980 in 254aa.
  
  
 0.835
PH0052
227aa long hypothetical fibrillarin-like pre-rRNA processing protein; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
 
 0.820
PH0101
481aa long hypothetical protein; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
  
 
 0.806
PH0057
168aa long hypothetical protein; Similar to owl:HPAE00058613 percent identity: 43.312 in 160aa; owl:MTCY1A1020 percent identity: 48.696 in 115aa; owl:MLCL58110 percent identity: 45.082 in 122aa. motif=zinc carboxypeptidases, zinc-binding regions signatures.
       0.775
PH1488
170aa long hypothetical protein.
 
 
 0.708
PH1426
336aa long hypothetical thioredoxin reductase; Similar to owl:BSZ940436 percent identity: 51.656 in 315aa; owl:AF0096221 percent identity: 49.667 in 313aa; Swiss_Prot:P50971 percent identity: 46.154 in 316aa. motif=pyridine nucleotide-disulphide oxidoreductases class-II active site.
  
  
 0.697
PH0114
316aa long hypothetical molybdenum cofactor biosynthesis protein; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family.
  
  
 0.658
Your Current Organism:
Pyrococcus horikoshii
NCBI taxonomy Id: 70601
Other names: P. horikoshii OT3, Pyrococcus horikoshii OT-3, Pyrococcus horikoshii OT3, Pyrococcus horikoshii str. OT3, Pyrococcus shinkaii OT3, Pyrococcus sp. OT3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.