STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PH0066328aa long hypothetical L-asparaginase; Similar to Swiss_Prot:P26900 percent identity: 40.373 in 326aa; Swiss_Prot:P18840 percent identity: 38.768 in 278aa; PIR:D64302 percent identity: 39.502 in 297aa. motif=asparaginase / glutaminase active sites signatures. (328 aa)    
Predicted Functional Partners:
PH1464
635aa long hypothetical protein; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
  
 
 0.926
PH0015
464aa long hypothetical L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
  
 
 0.923
PH0232
305aa long hypothetical L-asparaginase; Similar to owl:ECAE0001852 percent identity: 39.721 in 297aa; Swiss_Prot:P50287 percent identity: 40.141 in 295aa; Swiss_Prot:P30362 percent identity: 41.288 in 280aa. motif=ATP/GTP-binding site motif A (P-loop).
    
 0.922
PH1102
480aa long hypothetical asparagine synthetase; Similar to PIR:C64439 percent identity: 45.304 in 190aa.
    
 0.921
PH0771
391aa long hypothetical aspartate aminotransferase; Similar to PIR:A64300 percent identity: 48.098 in 386aa; PIR:JC4537 percent identity: 41.026 in 355aa; owl:TAX99521 percent identity: 40.390 in 363aa. motif=aminotransferases class-I pyridoxal-phosphate attachment site; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
    
 0.914
PH0670
228aa long hypothetical aspartate racemase; Similar to owl:D84067 percent identity: 70.982 in 225aa; PIR:S60208 percent identity: 32.161 in 200aa; Swiss_Prot:P29079 percent identity: 33.937 in 224aa. motif=aspartate and glutamate racemases signatures; Belongs to the aspartate/glutamate racemases family.
    
 0.911
PH1733
226aa long hypothetical aspartate racemase; Similar to Swiss_Prot:P03813 percent identity: 36.279 in 221aa; owl:D881893 percent identity: 43.651 in 128aa; owl:D84067 percent identity: 29.545 in 222aa.
    
 0.911
PH0720
308aa long hypothetical aspartate carbamoyltransferase catalytic chain; Similar to owl:PAU61765 percent identity: 92.532 in 308aa; PIR:D64497 percent identity: 58.503 in 297aa; owl:VSPYRBI1 percent identity: 55.593 in 302aa. motif=aspartate and ornithine carbamoyltransferases signature.
    
 0.904
PH0438
339aa long hypothetical adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
     
  0.900
PH0721
152aa long hypothetical aspartate carbamoyltransferase regulatory chain; Involved in allosteric regulation of aspartate carbamoyltransferase.
     
  0.900
Your Current Organism:
Pyrococcus horikoshii
NCBI taxonomy Id: 70601
Other names: P. horikoshii OT3, Pyrococcus horikoshii OT-3, Pyrococcus horikoshii OT3, Pyrococcus horikoshii str. OT3, Pyrococcus shinkaii OT3, Pyrococcus sp. OT3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.