STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PH0114316aa long hypothetical molybdenum cofactor biosynthesis protein; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. (316 aa)    
Predicted Functional Partners:
PH1811
159aa long hypothetical molybdenum cofactor biosynthesis protein; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
 
 0.999
PH0184
149aa long hypothetical molybdopterinconverting factor, subunit; Similar to owl:MTCY16429 percent identity: 38.525 in 122aa; owl:ATAC00233312 percent identity: 34.752 in 141aa; Swiss_Prot:P30749 percent identity: 40.171 in 117aa. motif=tonB-dependent receptor proteins signatures.
 
 
 0.938
PH1783
269aa long hypothetical protein; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
     
  0.900
PH0523
173aa long hypothetical molybdenum cofactor biosynthesis protein; Similar to owl:AF008220145 percent identity: 47.853 in 174aa; PIR:H64320 percent identity: 49.254 in 144aa. motif=molybdenum cofactor biosynthesis proteins signatures.
 
  
 0.889
PH0582
402aa long hypothetical molybdopterin biosynthesis moea protein; Similar to PIR:F64410 percent identity: 49.185 in 385aa; PIR:B64383 percent identity: 39.444 in 384aa; Swiss_Prot:P12281 percent identity: 38.776 in 299aa.
 
 0.850
PH0635
254aa long hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
  
  
 0.850
PH1647
396aa long hypothetical molybdopterin biosynthesis moeA protein; Similar to PIR:B64383 percent identity: 42.246 in 409aa; PIR:F64410 percent identity: 44.961 in 266aa; Swiss_Prot:P45210 percent identity: 34.933 in 398aa.
 
 0.832
PH0021
611aa long hypothetical protein; motif=ATP/GTP-binding site motif A (P-loop).
    
 0.831
PH0570
478aa long hypothetical pyruvate kinase; Similar to PIR:A57418 percent identity:76.037 in 217aa; PIR:S76677 percent identity:42.128 in 484aa; Swiss_Prot:Q02499 percent identity:43.991 in 475aa. motif=eukaryotic thiol (cysteine) proteases active sites; Belongs to the pyruvate kinase family.
 
  
  0.823
PH1012
165aa long hypothetical protein.
    
  0.813
Your Current Organism:
Pyrococcus horikoshii
NCBI taxonomy Id: 70601
Other names: P. horikoshii OT3, Pyrococcus horikoshii OT-3, Pyrococcus horikoshii OT3, Pyrococcus horikoshii str. OT3, Pyrococcus shinkaii OT3, Pyrococcus sp. OT3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.