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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PH0224523aa long hypothetical lysyl-tRNA synthetase; Similar to PIR:C64367 percent identity: 40.971 in 535aa. motif=aminoacyl-transfer RNA synthetases class-I signature. (523 aa)    
Predicted Functional Partners:
PH1408
226aa long hypothetical protein; Catalyzes the reversible phosphorylation of UMP to UDP.
     0.834
PH0225
301aa long hypothetical protein; motif=ATP/GTP-binding site motif A (P-loop).
       0.773
PH1006
480aa long hypothetical prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
  
  
 0.736
PH0002
155aa long hypothetical transcription termination-antitermination factor; Stimulates transcription elongation; Belongs to the archaeal Spt5 family.
  
    0.635
PH1265
192aa long hypothetical cytidylate kinase; Similar to PIR:H64381 percent identity: 61.628 in 176aa; owl:SARL34CDK2 percent identity: 43.713 in 169aa.
  
     0.511
PH1478
629aa long hypothetical arginyl-tRNA synthetase; Similar to PIR:F64329 percent identity: 40.975 in 639aa; Swiss_Prot:P43832 percent identity: 40.000 in 192aa. motif=aminoacyl-transfer RNA synthetases class-I signature.
 
   
 0.441
PH0256
377aa long hypothetical protein; Similar to owl:SS56KBFR33 percent identity: 33.134 in 364aa. motif=neutral zinc metallopeptidases, zinc-binding region signature.
 
     0.419
PH1011
375aa long hypothetical tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily.
   
  
 0.406
Your Current Organism:
Pyrococcus horikoshii
NCBI taxonomy Id: 70601
Other names: P. horikoshii OT3, Pyrococcus horikoshii OT-3, Pyrococcus horikoshii OT3, Pyrococcus horikoshii str. OT3, Pyrococcus shinkaii OT3, Pyrococcus sp. OT3
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