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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PH0243601aa long hypothetical glutamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (601 aa)    
Predicted Functional Partners:
PH0359
443aa long hypothetical glutamine synthetase; Probably involved in nitrogen metabolism via ammonium assimilation. Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
  
 
 0.968
PH0510
325aa long hypothetical protein.
 
 
0.966
PH0240
449aa long hypothetical amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
 
  
0.949
PH1210
453aa long hypothetical phospho-sugar mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
 
 0.946
PH1955
227aa long hypothetical phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL an [...]
    
 0.934
PH0876
472aa long hypothetical glutamate synthase small chain; Similar to owl:D86223 percent identity: 76.972 in 476aa; owl:ECAE0003335 percent identity: 39.052 in 457aa; Swiss_Prot:P09832 percent identity: 37.251 in 466aa.
    
 0.926
PH1873
476aa long hypothetical glutamate synthase small chain; Similar to owl:D86223 percent identity: 82.553 in 472aa; PIR:JC5184 percent identity: 39.002 in 460aa; Swiss_Prot:P09832 percent identity: 36.947 in 472aa.
    
 0.926
PH1459
310aa long hypothetical fructokinase; Similar to Swiss_Prot:P37829 percent identity: 34.118 in 261aa; owl:BVU37838 percent identity: 36.525 in 301aa; owl:LEU62329 percent identity: 37.500 in 270aa. motif=pfkB family of carbohydrate kinases signatures.
  
 
 0.918
PH0925
464aa long hypothetical mannose-1-phosphate guanylyl transferase; Similar to Swiss_Prot:P29956 percent identity:49.776 in 474aa; owl:YEU4685916 percent identity:45.721 in 470aa; PIR:E56146 percent identity:44.371 in 474aa; Belongs to the mannose-6-phosphate isomerase type 2 family.
    
 0.916
PH1956
192aa long hypothetical protein.
    
  0.901
Your Current Organism:
Pyrococcus horikoshii
NCBI taxonomy Id: 70601
Other names: P. horikoshii OT3, Pyrococcus horikoshii OT-3, Pyrococcus horikoshii OT3, Pyrococcus horikoshii str. OT3, Pyrococcus shinkaii OT3, Pyrococcus sp. OT3
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