Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PH0322219aa long hypothetical protein. (219 aa)    
Predicted Functional Partners:
PH0321
253aa long hypothetical protein.
       0.920
PH0320
177aa long hypothetical phosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
       0.842
PH0323
438aa long hypothetical phosphoribosylamide--glycine ligase; Similar to PIR:A64417 percent identity: 55.478 in 442aa; owl:HUMRPS4 percent identity: 33.738 in 424aa; Swiss_Prot:P12039 percent identity: 33.819 in 352aa. motif=prokaryotic membrane lipoprotein lipid attachment site.
       0.830
PH0324
383aa long hypothetical protein; Similar to PIR:H64316 percent identity: 44.847 in 382aa.
       0.822
PH1955
227aa long hypothetical phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL an [...]
       0.576
PH0325
364aa long hypothetical protein.
       0.401
PH0326
1003aa long hypothetical protein.
       0.401
PH0328
320aa long hypothetical protein.
       0.401
PH0329
317aa long hypothetical protein; Similar to owl:BSU511154 percent identity:51.342 in 303aa; PIR:S75782 percent identity:49.823 in 286aa; PIR:S74593 percent identity:41.751 in 297aa.
       0.401
PH0331
406aa long hypothetical protein.
       0.401
Your Current Organism:
Pyrococcus horikoshii
NCBI taxonomy Id: 70601
Other names: P. horikoshii OT3, Pyrococcus horikoshii OT-3, Pyrococcus horikoshii OT3, Pyrococcus horikoshii str. OT3, Pyrococcus shinkaii OT3, Pyrococcus sp. OT3
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