close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PH0369350aa long hypothetical galactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). (350 aa)    
Predicted Functional Partners:
PH0365
327aa long hypothetical galactose-1-phosphate uridyltransferase; Similar to owl:MTCY19H51 percent identity: 33.918 in 173aa; Swiss_Prot:P31764 percent identity: 29.730 in 226aa; owl:HIGALTKMR1 percent identity: 29.279 in 226aa. motif=tubulin-beta mRNA autoregulation signal.
 0.999
PH1590
264aa long hypothetical protein; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
     
 0.836
PH0367
457aa long hypothetical protein.
     
 0.827
PH0368
364aa long hypothetical protein.
       0.819
PHS052
87aa long hypothetical 50S ribosomal protein L35; Similar to Swiss_Prot:P20299 percent identity: 91.954 in 87aa; Swiss_Prot:P41056 percent identity: 38.095 in 92aa; Swiss_Prot:P05744 percent identity: 36.905 in 92aa. motif=ribosomal protein L35Ae signature; Belongs to the eukaryotic ribosomal protein eL33 family.
      
 0.744
PH0159
162aa long hypothetical protein; Probable biotin transporter; Belongs to the BioY family.
      
 0.709
PH0147
235aa long hypothetical biotin--[acetyl-CoA-carboxylase] ligase; Similar to Swiss_Prot:P42975 percent identity: 36.245 in 250aa; owl:BSU20445 percent identity: 36.245 in 250aa.
  
  
 0.698
PH1881
371aa long hypothetical protein; Similar to owl:BSY0947623 percent identity:28.399 in 344aa.
  
 
 0.683
PH1882
335aa long hypothetical glucose-fructose oxidoreductase; Similar to owl:ZMGFO percent identity:28.788 in 201aa; PIR:S70672 percent identity:29.317 in 258aa.
  
 
 0.683
PH0511
778aa long hypothetical beta-galactosidase precursor; Exo-type enzyme that specifically cleaves the non-reducing terminal glycosidic bond of chitooligosaccharides. Catalyzes the hydrolysis of GlcN-GlcNAc to glucosamine (GlcN) and N-acetylglucosamine (GlcNAc). Involved in chitin degradation. Can also hydrolyze chitosan and chitooligosaccharides of various chain lengths ; Belongs to the glycosyl hydrolase 35 family.
 
  
 0.653
Your Current Organism:
Pyrococcus horikoshii
NCBI taxonomy Id: 70601
Other names: P. horikoshii OT3, Pyrococcus horikoshii OT-3, Pyrococcus horikoshii OT3, Pyrococcus horikoshii str. OT3, Pyrococcus shinkaii OT3, Pyrococcus sp. OT3
Server load: medium (58%) [HD]