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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PH0724274aa long hypothetical protein. (274 aa)    
Predicted Functional Partners:
PH1622
559aa long hypothetical DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
 0.984
PH0197
361aa long hypothetical protein; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of both single-stranded RNA (ssRNA) and single-stranded DNA (ssDNA). Exhibits a strong preference for ssRNA.
   
 0.845
PH0725
265aa long hypothetical diphthine synthase; S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis.
     
 0.787
PHS056
77aa long hypothetical DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoP/eukaryotic RPC10 RNA polymerase subunit family.
   
 0.785
PHS044
82aa long hypothetical DNA-directed RNA polymerase subunit Hprotein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family.
   
  0.783
PH1546
1117aa long hypothetical DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.781
PH1632
119aa long hypothetical DNA-directed RNA polymerase subunit N; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family.
   
  0.726
PH1637
261aa long hypothetical DNA-directed RNA polymerase subunit D; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoD/eukaryotic RPB3 RNA polymerase subunit family.
  
 0.723
PH0664
110aa long hypothetical transcription-associated protein; Similar to PIR:A55263 percent identity: 65.138 in 110aa; PIR:C64443 percent identity: 47.222 in 110aa. motif=TFIIS zinc ribbon domain signature; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
  
 0.709
PH1329
912aa long hypothetical ATP-dependent helicase; Similar to PIR:G64336 percent identity:37.500 in 646aa; owl:SS56KBFR9 percent identity:34.457 in 573aa. motif=ATP/GTP-binding site motif A (P-loop).
 
    0.657
Your Current Organism:
Pyrococcus horikoshii
NCBI taxonomy Id: 70601
Other names: P. horikoshii OT3, Pyrococcus horikoshii OT-3, Pyrococcus horikoshii OT3, Pyrococcus horikoshii str. OT3, Pyrococcus shinkaii OT3, Pyrococcus sp. OT3
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