STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PH0759390aa long hypothetical protein; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). (390 aa)    
Predicted Functional Partners:
PH1884
231aa long hypothetical triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
    
 0.985
PH1830
334aa long hypothetical glyceraldehyde-3-phosphate dehydrogenase; Similar to Swiss_Prot:P20286 percent identity: 90.719 in 334aa; Swiss_Prot:P10618 percent identity: 56.061 in 334aa; Swiss_Prot:P19315 percent identity: 57.751 in 335aa. motif=glyceraldehyde 3-phosphate dehydrogenase active site.
  
 
 0.981
PH0082
281aa long hypothetical protein; Similar to PIR:H64349 percent identity: 36.782 in 274aa; Belongs to the DeoC/FbaB aldolase family.
    
 0.978
PH1942
428aa long hypothetical phosphoglycerate dehydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
    
 0.959
PH0457
653aa long hypothetical protein; Similar to PIR:H64447 percent identity: 48.739 in 631aa. motif=crystallins beta and gamma 'Greek key' motif signature; eukaryotic thiol (cysteine) proteases active sites.
 
  
 0.943
PH1459
310aa long hypothetical fructokinase; Similar to Swiss_Prot:P37829 percent identity: 34.118 in 261aa; owl:BVU37838 percent identity: 36.525 in 301aa; owl:LEU62329 percent identity: 37.500 in 270aa. motif=pfkB family of carbohydrate kinases signatures.
     
 0.916
PH0589
457aa long hypothetical protein; Catalyzes the ADP-dependent phosphorylation of D-glucose to D-glucose 6-phosphate and glucosamine to glucosamine 6-phosphate.
     
 0.909
PH1645
450aa long hypothetical protein; Catalyzes the phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate using ADP as the phosphate donor.
     
 0.909
PH1956
192aa long hypothetical protein.
    
 0.909
PH1938
406aa long hypothetical D-arabino 3-hexulose 6-phosphate formaldehyde lyase; Similar to owl:MAGHPS percent identity: 44.608 in 206aa; Swiss_Prot:P42405 percent identity: 46.203 in 159aa; Swiss_Prot:P42404 percent identity: 41.808 in 186aa.
     
 0.902
Your Current Organism:
Pyrococcus horikoshii
NCBI taxonomy Id: 70601
Other names: P. horikoshii OT3, Pyrococcus horikoshii OT-3, Pyrococcus horikoshii OT3, Pyrococcus horikoshii str. OT3, Pyrococcus shinkaii OT3, Pyrococcus sp. OT3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.