STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PH0781526aa long hypothetical alanine transport protein; Similar to Swiss_Prot:P44917 percent identity: 42.202 in 517aa; owl:HPAE0006036 percent identity: 43.736 in 524aa; Swiss_Prot:P44555 percent identity: 38.095 in 311aa. motif=sodium:alanine symporter family signature. (526 aa)    
Predicted Functional Partners:
PH0782
474aa long hypothetical 4-aminobutyrate aminotransferase; Catalyzes the interconversion of L-alanine and D-alanine, and L-serine and D-serine. Has weak activity with valine and threonine.
     
 0.936
PHS056
77aa long hypothetical DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoP/eukaryotic RPC10 RNA polymerase subunit family.
      
 0.701
PH0138
466aa long hypothetical 4-aminobutyrate aminotransferase; Amino-acid racemase able to utilize a broad range of substrates. Can use Met, Leu, Phe, Ala, Ser, Ile, Val, Trp, Tyr and Thr. Is mostly active with Phe, Leu, Met and Tyr, followed by Ile, Thr and Trp. Has weaker activity with Val, Ser and Ala. Shows no activity toward Pro, Asp, Glu, Arg, His, Gln and Asn.
     
 0.652
PH1423
454aa long hypothetical 4-aminobutyrate aminotransferase; Similar to owl:D5045389 percent identity: 38.539 in 406aa; Swiss_Prot:P30268 percent identity: 39.552 in 409aa; Swiss_Prot:P40829 percent identity: 39.646 in 409aa. motif=aminotransferases class-III pyridoxal-phosphate attachment site; ATP/GTP-binding s; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
 0.652
PH1501
438aa long hypothetical aminotransferase; Similar to owl:D5045389 percent identity: 38.287 in 401aa; Swiss_Prot:P30268 percent identity: 36.409 in 409aa; Swiss_Prot:P22256 percent identity: 36.750 in 409aa. motif=aminotransferases class-III pyridoxal-phosphate attachment site; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
 0.649
PH1020
438aa long hypothetical aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp).
      
 0.648
PH0032
370aa long hypothetical protein.
 
    0.615
PH1372
521aa long hypothetical sodium-dependent transporter; Similar to PIR:F64464 percent identity: 28.918 in 488aa.
 
  
 0.597
PH1295
425aa long hypothetical proton glutamate symport protein; Sodium-dependent, high-affinity amino acid transporter that mediates aspartate uptake (Ref.11). Has only very low glutamate transport activity. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions, resulting in electrogenic transport (Ref.11). Na(+) binding enhances the affinity for aspartate. Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport. In contrast to mammalian homologs, tran [...]
  
  
 0.591
PH1361
537aa long hypothetical proline permease; Similar to owl:BSU924662 percent identity: 35.581 in 436aa; owl:HPAE0005273 percent identity: 36.406 in 440aa; owl:D5045324 percent identity: 37.692 in 396aa. motif=prokaryotic membrane lipoprotein lipid attachment site; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  
  
 0.587
Your Current Organism:
Pyrococcus horikoshii
NCBI taxonomy Id: 70601
Other names: P. horikoshii OT3, Pyrococcus horikoshii OT-3, Pyrococcus horikoshii OT3, Pyrococcus horikoshii str. OT3, Pyrococcus shinkaii OT3, Pyrococcus sp. OT3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.