STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PH0986255aa long hypothetical lactam utilization protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. (255 aa)    
Predicted Functional Partners:
PH0987
225aa long hypothetical protein; Similar to Swiss_Prot:P42967 percent identity: 50.000 in 224aa; owl:ECAE0001748 percent identity: 45.349 in 173aa; Swiss_Prot:P44299 percent identity: 38.164 in 209aa.
  
 0.999
PH0988
331aa long hypothetical protein; Similar to Swiss_Prot:P44298 percent identity: 34.768 in 304aa; owl:ECAE0001749 percent identity: 33.770 in 314aa; owl:MTCY6A46 percent identity: 32.014 in 283aa.
  
 0.998
PH0359
443aa long hypothetical glutamine synthetase; Probably involved in nitrogen metabolism via ammonium assimilation. Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
   
 
  0.808
PH1593
422aa long hypothetical glutamate dehydrogenase; Similar to owl:A47410 percent identity: 96.429 in 420aa; Swiss_Prot:P80319 percent identity: 95.952 in 420aa; owl:THCGLUDEHY percent identity: 87.799 in 419aa. motif=glu / Leu / Phe / Val dehydrogenases active site; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
    
  0.807
PH0876
472aa long hypothetical glutamate synthase small chain; Similar to owl:D86223 percent identity: 76.972 in 476aa; owl:ECAE0003335 percent identity: 39.052 in 457aa; Swiss_Prot:P09832 percent identity: 37.251 in 466aa.
     
  0.800
PH1873
476aa long hypothetical glutamate synthase small chain; Similar to owl:D86223 percent identity: 82.553 in 472aa; PIR:JC5184 percent identity: 39.002 in 460aa; Swiss_Prot:P09832 percent identity: 36.947 in 472aa.
     
  0.800
PH1955
227aa long hypothetical phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL an [...]
     
  0.800
PH0627
250aa long hypothetical protein; Similar to PIR:G64142 percent identity: 38.525 in 247aa; owl:ECAE0001747 percent identity: 40.909 in 249aa.
    
 0.791
PH0985
238aa long hypothetical arylmalonate decarboxylase; Similar to Swiss_Prot:Q05115 percent identity: 30.806 in 214aa.
       0.752
PH1935
266aa long hypothetical protein.
  
    0.718
Your Current Organism:
Pyrococcus horikoshii
NCBI taxonomy Id: 70601
Other names: P. horikoshii OT3, Pyrococcus horikoshii OT-3, Pyrococcus horikoshii OT3, Pyrococcus horikoshii str. OT3, Pyrococcus shinkaii OT3, Pyrococcus sp. OT3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.