STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PH1002352aa long hypothetical protein; Similar to PIR:C64503 percent identity: 54.480 in 286aa; Belongs to the UPF0282 family. (352 aa)    
Predicted Functional Partners:
PH1003
873aa long hypothetical helicase; Similar to PIR:E64496 percent identity: 54.748 in 677aa; Swiss_Prot:P50830 percent identity: 38.028 in 375aa; PIR:S70120 percent identity: 36.979 in 407aa.
       0.773
PH1004
252aa long hypothetical protein.
       0.610
PH1059
141aa long hypothetical protein; Similar to PIR:G64325 percent identity: 50.820 in 122aa.
  
   
 0.608
PH1379
229aa long hypothetical protein; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA.
 
     0.604
PH1000
355aa long hypothetical protein.
       0.556
PH1001
150aa long hypothetical protein; Similar to PIR:B64408 percent identity: 39.252 in 108aa. motif=HIT family signature.
       0.556
PH0080
355aa long hypothetical protein; Similar to PIR:E64352 percent identity: 62.281 in 346aa.
  
     0.521
PHS053
93aa long hypothetical protein; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes; Belongs to the histone-like Alba family.
  
   
 0.491
PH1010
138aa long hypothetical protein; Similar to PIR:C64495 percent identity:43.750 in 134aa; Belongs to the UPF0201 family.
  
   
 0.486
PH1876
154aa long hypothetical protein; Similar to PIR:F64326 percent identity: 37.500 in 128aa.
  
   
 0.455
Your Current Organism:
Pyrococcus horikoshii
NCBI taxonomy Id: 70601
Other names: P. horikoshii OT3, Pyrococcus horikoshii OT-3, Pyrococcus horikoshii OT3, Pyrococcus horikoshii str. OT3, Pyrococcus shinkaii OT3, Pyrococcus sp. OT3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.