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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PH1137407aa long hypothetical RNA methyltransferase; Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (407 aa)    
Predicted Functional Partners:
PH1941
186aa long hypothetical maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
     0.917
PH1858
253aa long hypothetical protein; Similar to PIR:F64316 percent identity: 47.059 in 269aa; owl:MTCY26113 percent identity: 36.145 in 254aa; owl:S72844 percent identity: 35.887 in 259aa.
   
  
 0.654
PH1138
618aa long hypothetical indolepyruvate ferredoxin oxidoreductase alpha subunit; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
       0.646
PH0788
816aa long hypothetical protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
  
    0.569
PH1320
357aa long hypothetical protein; Similar to PIR:G64475 percent identity: 53.395 in 332aa; owl:S61973 percent identity: 31.615 in 291aa. motif=ATP/GTP-binding site motif A (P-loop).
   
    0.540
PH1829
381aa long hypothetical N2,N2-dimethylguanosine tRNA methyltransferase; Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
   
  
 0.504
PH1132
426aa long hypothetical GTP-binding protein hflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
 
  
 0.496
PH1139
494aa long hypothetical protein; Similar to owl:AF008220136 percent identity: 29.550 in 500aa. motif=uncharacterized protein family UPF0006 signatures.
       0.494
PH1823
290aa long hypothetical dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
  
  
 0.488
PH0709
161aa long hypothetical protein; Toxic component of a type II toxin-antitoxin (TA) system (Potential). Processes pre-16S-rRNA at its 3' end (the D-site) to yield the mature 3' end; Belongs to the PINc/VapC protein family.
   
    0.487
Your Current Organism:
Pyrococcus horikoshii
NCBI taxonomy Id: 70601
Other names: P. horikoshii OT3, Pyrococcus horikoshii OT-3, Pyrococcus horikoshii OT3, Pyrococcus horikoshii str. OT3, Pyrococcus shinkaii OT3, Pyrococcus sp. OT3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.