STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PH1322401aa long hypothetical aspartate aminotransferase; Similar to owl:HIU3271411 percent identity: 39.516 in 378aa; owl:MTCY2793 percent identity: 40.811 in 377aa; owl:D9086011 percent identity: 38.462 in 397aa. (401 aa)    
Predicted Functional Partners:
PH1593
422aa long hypothetical glutamate dehydrogenase; Similar to owl:A47410 percent identity: 96.429 in 420aa; Swiss_Prot:P80319 percent identity: 95.952 in 420aa; owl:THCGLUDEHY percent identity: 87.799 in 419aa. motif=glu / Leu / Phe / Val dehydrogenases active site; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.927
PH1727
361aa long hypothetical 2-isopropylmalate synthase; Catalyzes the aldol-type condensation of 2-oxoglutarate with acetyl-CoA to yield homocitrate. Carries out the first step of the alpha-aminoadipate (AAA) lysine biosynthesis pathway. Belongs to the alpha-IPM synthase/homocitrate synthase family. Homocitrate synthase LYS20/LYS21 subfamily.
  
 
 0.925
PH0771
391aa long hypothetical aspartate aminotransferase; Similar to PIR:A64300 percent identity: 48.098 in 386aa; PIR:JC4537 percent identity: 41.026 in 355aa; owl:TAX99521 percent identity: 40.390 in 363aa. motif=aminotransferases class-I pyridoxal-phosphate attachment site; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
  
  
 
0.909
PH1722
323aa long hypothetical 3-isopropylmalate dehydrogenase; May play a dual role in glutamate and lysine biosynthesis in vivo. Uses isocitrate and homoisocitrate at near equal efficiency and preferentially uses NAD over NADP.
  
 
 0.850
PH1661
281aa long hypothetical ferredoxin oxidoreductase beta subunit; Similar to PIR:A64367 percent identity: 54.373 in 263aa; owl:HPAE0005725 percent identity: 44.697 in 265aa; PIR:S22397 percent identity: 43.011 in 186aa.
  
 
 0.820
PH1665
284aa long hypothetical ferredoxin oxidoreductase beta subunit; Similar to PIR:A64367 percent identity: 57.303 in 268aa; owl:HPAE0005725 percent identity: 45.643 in 242aa; PIR:JC4920 percent identity: 45.161 in 187aa.
  
 
 0.820
PH1662
385aa long hypothetical ferredoxin oxidoreductase alpha subunit; Similar to PIR:E64334 percent identity: 57.939 in 368aa; owl:HPAE0005724 percent identity: 40.947 in 366aa; PIR:S22396 percent identity: 46.108 in 167aa.
  
 
 0.819
PH1666
408aa long hypothetical ferredoxin oxidoreductase alpha subunit; Similar to PIR:E64334 percent identity: 56.630 in 371aa; owl:HPAE0005724 percent identity: 42.486 in 351aa; PIR:S22396 percent identity: 34.848 in 343aa. motif=prokaryotic membrane lipoprotein lipid attachment site.
  
 
 0.819
PH1660
185aa long hypothetical ferredoxin oxidoreductase gamma subunit; Similar to PIR:H64366 percent identity: 58.333 in 181aa.
    
 0.816
PH1663
170aa long hypothetical ferredoxin oxidoreductase gamma subunit; Similar to PIR:H64366 percent identity: 48.824 in 177aa.
    
 0.816
Your Current Organism:
Pyrococcus horikoshii
NCBI taxonomy Id: 70601
Other names: P. horikoshii OT3, Pyrococcus horikoshii OT-3, Pyrococcus horikoshii OT3, Pyrococcus horikoshii str. OT3, Pyrococcus shinkaii OT3, Pyrococcus sp. OT3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.