STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PH1472197aa long hypothetical protein. (197 aa)    
Predicted Functional Partners:
PH1473
119aa long hypothetical protein.
     
 0.965
PH1474
267aa long hypothetical protein.
     
 0.957
PH1905
281aa long hypothetical protein; Similar to PIR:E64316 percent identity: 51.311 in 273aa; owl:SS100KBFR82 percent identity: 37.453 in 276aa.
     
 0.829
PH1229
239aa long hypothetical protein; DNA repair enzyme that is part of the base excision repair (BER) pathway; protects from oxidative damage by removing the major product of DNA oxidation, 8-oxoguanine (GO), from single- and double- stranded DNA substrates.
      
 0.769
PH0002
155aa long hypothetical transcription termination-antitermination factor; Stimulates transcription elongation; Belongs to the archaeal Spt5 family.
      
 0.664
PH1471
244aa long hypothetical protein; Similar to PIR:H64492 percent identity: 52.752 in 221aa.
       0.661
PH0834
571aa long hypothetical oxaloacetate decarboxylase alpha chain; Similar to PIR:F64453 percent identity: 56.150 in 571aa; owl:LPOADAGEN percent identity: 47.518 in 593aa; Swiss_Prot:Q03030 percent identity: 46.032 in 590aa. motif=biotin-requiring enzymes attachment site.
  
    0.564
PH1475
351aa long hypothetical glycerol 1-phaphate dehydrogenase; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. Belongs to the glycerol-1-phosphate dehydrogenase family.
       0.475
PH1074
277aa long hypothetical protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. It can use ATP and other nucleoside triphosphates (GTP,UTP) as well as inorganic polyphosphate (poly(P)) as a source of phosphorus. NAD is the preferred substrate for the kinase, but NADH can also be used as phosphoryl acceptor.
  
    0.454
PH1242
262aa long hypothetical pseudouridylate synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family.
  
  
 0.410
Your Current Organism:
Pyrococcus horikoshii
NCBI taxonomy Id: 70601
Other names: P. horikoshii OT3, Pyrococcus horikoshii OT-3, Pyrococcus horikoshii OT3, Pyrococcus horikoshii str. OT3, Pyrococcus shinkaii OT3, Pyrococcus sp. OT3
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