STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PH1562417aa long hypothetical protein. (417 aa)    
Predicted Functional Partners:
PH1563
301aa long hypothetical typeII DNA topoisomerase subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family.
       0.819
PH1564
564aa long hypothetical typeII DNA topoisomerase subunit B; Relaxes both positive and negative superturns and exhibits a strong decatenase activity.
       0.613
PH1566
219aa long hypothetical protein; Similar to PIR:C64355 percent identity: 50.575 in 177aa.
       0.613
PH1567
266aa long hypothetical protein; Similar to PIR:D64355 percent identity: 38.565 in 231aa; Swiss_Prot:Q03021 percent identity: 38.095 in 176aa; Swiss_Prot:P34649 percent identity: 34.842 in 229aa. motif=protein kinases signatures and profile; RIO1/ZK632.3/MJ0444 family signature.
       0.613
PH1568
116aa long hypothetical translation initiation factor eIF-1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity).
       0.613
PH0101
481aa long hypothetical protein; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
  
    0.412
Your Current Organism:
Pyrococcus horikoshii
NCBI taxonomy Id: 70601
Other names: P. horikoshii OT3, Pyrococcus horikoshii OT-3, Pyrococcus horikoshii OT3, Pyrococcus horikoshii str. OT3, Pyrococcus shinkaii OT3, Pyrococcus sp. OT3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.