Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
PH1568116aa long hypothetical translation initiation factor eIF-1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity). (116 aa)    
Predicted Functional Partners:
PH0605
140aa long hypothetical translation initiation factor eIF-2 beta; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA; Belongs to the eIF-2-beta/eIF-5 family.
 
 0.997
PH1706
411aa long hypothetical translation initiation factor eIF-2 gamma; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
 
 0.997
PH0961
275aa long hypothetical translation initiation factor eIF-2 alpha chain; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA; Belongs to the eIF-2-alpha family.
  
 0.996
PH1633
135aa long hypothetical 30S ribosomal protein S9; Similar to Swiss_Prot:P54024 percent identity: 64.925 in 134aa; Swiss_Prot:P05763 percent identity: 51.908 in 133aa; owl:SS56KBFR53 percent identity: 49.242 in 134aa. motif=ribosomal protein S9 signature; Belongs to the universal ribosomal protein uS9 family.
  
 0.995
PH1774
132aa long hypothetical 30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
 
 0.995
PH1542
150aa long hypothetical 30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family.
 
 0.993
PH1567
266aa long hypothetical protein; Similar to PIR:D64355 percent identity: 38.565 in 231aa; Swiss_Prot:Q03021 percent identity: 38.095 in 176aa; Swiss_Prot:P34649 percent identity: 34.842 in 229aa. motif=protein kinases signatures and profile; RIO1/ZK632.3/MJ0444 family signature.
  
 
 0.989
PH1764
130aa long hypothetical 30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.
 
 0.989
PH1756
155aa long hypothetical 50S ribosomal protein L30; Similar to Swiss_Prot:P54046 percent identity: 66.667 in 152aa; Swiss_Prot:P14035 percent identity: 54.000 in 152aa; GENPEPT:Y07778 percent identity: 43.709 in 153aa. motif=ribosomal protein L30 signature.
 
 0.988
PHS047
56aa long hypothetical 30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles.
  
 0.988
Your Current Organism:
Pyrococcus horikoshii
NCBI taxonomy Id: 70601
Other names: P. horikoshii OT3, Pyrococcus horikoshii OT-3, Pyrococcus horikoshii OT3, Pyrococcus horikoshii str. OT3, Pyrococcus shinkaii OT3, Pyrococcus sp. OT3
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