Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PH1616233aa long hypothetical protein; Similar to PIR:H64413 percent identity: 46.491 in 246aa. (233 aa)    
Predicted Functional Partners:
PH1517
460aa long hypothetical protein; Similar to PIR:F64373 percent identity: 47.204 in 459aa; owl:ECOK12RIII17 percent identity: 33.028 in 455aa; owl:ECAE00034410 percent identity: 33.028 in 455aa.
       0.671
PH0900
902aa long hypothetical protein.
 
 
 0.636
PH0724
274aa long hypothetical protein.
   
 0.593
PH1414
129aa long hypothetical protein.
       0.576
PH0344
186aa long hypothetical protein; Similar to PIR:H64414 percent identity: 44.886 in 179aa. motif=ATP/GTP-binding site motif A (P-loop).
   
 0.571
PH0611
252aa long hypothetical protein; Similar to Swiss_Prot:P46577 percent identity:30.736 in 238aa. motif=ATP/GTP-binding site motif A (P-loop).
   
 0.571
PH1615
420aa long hypothetical protein; Similar to PIR:G64312 percent identity: 46.724 in 374aa.
       0.516
PH0017
549aa long hypothetical thermophilic factor; Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity; Belongs to the TCP-1 chaperonin family.
  
 
 0.513
PH0961
275aa long hypothetical translation initiation factor eIF-2 alpha chain; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA; Belongs to the eIF-2-alpha family.
   
 
 0.501
PH1267
335aa long hypothetical protein; Similar to PIR:G64366 percent identity: 49.669 in 303aa; PIR:S74557 percent identity: 37.751 in 265aa.
 
 
 0.494
Your Current Organism:
Pyrococcus horikoshii
NCBI taxonomy Id: 70601
Other names: P. horikoshii OT3, Pyrococcus horikoshii OT-3, Pyrococcus horikoshii OT3, Pyrococcus horikoshii str. OT3, Pyrococcus shinkaii OT3, Pyrococcus sp. OT3
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