close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PH1688352aa long hypothetical protein. (352 aa)    
Predicted Functional Partners:
PH1690
140aa long hypothetical protein; Motif=prokaryotic membrane lipoprotein lipid attachment site.
       0.572
PH0937
383aa long hypothetical protein; Catalyzes the decarboxylation of L-aspartate to produce beta- alanine, and the decarboxylation of L-glutamate to produce 4- aminobutanoate. Can also use cysteate and cysteine sulfite, but not L- tyrosine. Specific activities toward L-aspartate and cysteate are higher than toward L-glutamate.
 
   
 0.536
PH0642
262aa long hypothetical protein; Similar to owl:PBU4258077 percent identity:40.397 in 157aa; owl:HPAE0005494 percent identity:38.136 in 257aa; Swiss_Prot:P55176 percent identity:32.540 in 265aa. motif=ATP/GTP-binding site motif A (P-loop).
 
  
 0.487
PH1722
323aa long hypothetical 3-isopropylmalate dehydrogenase; May play a dual role in glutamate and lysine biosynthesis in vivo. Uses isocitrate and homoisocitrate at near equal efficiency and preferentially uses NAD over NADP.
  
  
 0.424
Your Current Organism:
Pyrococcus horikoshii
NCBI taxonomy Id: 70601
Other names: P. horikoshii OT3, Pyrococcus horikoshii OT-3, Pyrococcus horikoshii OT3, Pyrococcus horikoshii str. OT3, Pyrococcus shinkaii OT3, Pyrococcus sp. OT3
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.