STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PH1807463aa long hypothetical DNA damage-inducible protein; Similar to PIR:JC4561 percent identity: 76.944 in 362aa; PIR:JC4562 percent identity: 82.796 in 93aa; owl:HPAE0005886 percent identity: 32.800 in 382aa. motif=crystallins beta and gamma 'Greek key' motif signature. (463 aa)    
Predicted Functional Partners:
PH0951
283aa long hypothetical 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
  
  
 0.833
PH1009
191aa long hypothetical TATA-binding protein (transcription initiation factor TFIID); General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation (By similarity).
   
  
 0.614
PH1830
334aa long hypothetical glyceraldehyde-3-phosphate dehydrogenase; Similar to Swiss_Prot:P20286 percent identity: 90.719 in 334aa; Swiss_Prot:P10618 percent identity: 56.061 in 334aa; Swiss_Prot:P19315 percent identity: 57.751 in 335aa. motif=glyceraldehyde 3-phosphate dehydrogenase active site.
  
  
 0.606
PH1806
252aa long hypothetical protein; Similar to PIR:C64368 percent identity:32.143 in 237aa. motif=ATP/GTP-binding site motif A (P-loop).
       0.516
PH0911
257aa long hypothetical protein; motif=ABC-2 type transport system integral membrane proteins signature.
  
  
 0.435
PH0820
312aa long hypothetical ATP-binding protein; Similar to owl:SS100KBFR62 percent identity: 41.391 in 308aa. motif=ABC transporters family signature; ATP/GTP-binding site motif A (P-loop).
  
  
 0.427
PH0913
324aa long hypothetical resistance ATP-binding protein; Similar to owl:SS100KBFR62 percent identity: 45.833 in 317aa; owl:SAU435372 percent identity: 38.926 in 303aa; PIR:S32908 percent identity: 47.368 in 229aa. motif=ABC transporters family signature; ATP/GTP-binding site motif A (P-loop).
  
  
 0.427
PH1230
253aa long hypothetical ATP-binding transport protein; Similar to PIR:S76626 percent identity:42.202 in 219aa; Swiss_Prot:P46903 percent identity:32.877 in 220aa; Swiss_Prot:P55339 percent identity:35.443 in 239aa. motif=ATP/GTP-binding site motif A (P-loop).
  
  
 0.427
PH1366
308aa long hypothetical ATP-binding transport protein; Similar to owl:D785084 percent identity: 40.367 in 218aa; Swiss_Prot:P54592 percent identity: 42.361 in 297aa. motif=ABC transporters family signature; ATP/GTP-binding site motif A (P-loop).
  
  
 0.427
PH1490
222aa long hypothetical transport protein; Similar to PIR:S42931 percent identity:29.949 in 204aa; PIR:S42927 percent identity:30.457 in 204aa. motif=ABC transporters family signature; ATP/GTP-binding site motif A (P-loop).
  
  
 0.427
Your Current Organism:
Pyrococcus horikoshii
NCBI taxonomy Id: 70601
Other names: P. horikoshii OT3, Pyrococcus horikoshii OT-3, Pyrococcus horikoshii OT3, Pyrococcus horikoshii str. OT3, Pyrococcus shinkaii OT3, Pyrococcus sp. OT3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.