STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PH1845296aa long hypothetical ribokinase; Similar ot Swiss_Prot:P44331 percent identity:29.749 in 298aa. motif=pfkB family of carbohydrate kinases signatures; Belongs to the carbohydrate kinase PfkB family. (296 aa)    
Predicted Functional Partners:
PH1844
381aa long hypothetical protein; Similar to PIR:F64500 percent identity: 31.989 in 390aa.
 
  
 0.784
PH1987
324aa long hypothetical O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.
     
 0.775
PH1843
310aa long hypothetical protein.
       0.668
PH1474
267aa long hypothetical protein.
  
  
 0.656
PH1882
335aa long hypothetical glucose-fructose oxidoreductase; Similar to owl:ZMGFO percent identity:28.788 in 201aa; PIR:S70672 percent identity:29.317 in 258aa.
 
  
 0.565
PH1881
371aa long hypothetical protein; Similar to owl:BSY0947623 percent identity:28.399 in 344aa.
 
  
 0.564
PH0770
154aa long hypothetical protein; Motif=mitochondrial energy transfer proteins signature.
      
 0.553
PH0438
339aa long hypothetical adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.536
PH1691
256aa long hypothetical protein.
  
 
 0.532
PH1842
172aa long hypothetical protein; Similar to owl:WHTHSP169C percent identity:37.864 in 104aa; owl:OSU81385 percent identity:37.864 in 104aa; Belongs to the small heat shock protein (HSP20) family.
     
 0.494
Your Current Organism:
Pyrococcus horikoshii
NCBI taxonomy Id: 70601
Other names: P. horikoshii OT3, Pyrococcus horikoshii OT-3, Pyrococcus horikoshii OT3, Pyrococcus horikoshii str. OT3, Pyrococcus shinkaii OT3, Pyrococcus sp. OT3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.