Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ilvA | metA | PANA_3825 | PANA_0232 | IlvA; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | MetA; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family. | 0.818 |
| ilvA | metB | PANA_3825 | PANA_3849 | IlvA; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | MetB; Cystathionine gamma-synthase; Similar to Pantoea sp. At-9b, O-succinylhomoserine (thiol)-lyase (NCBI: ZP_05730335.1); COG: Amino acid transport and metabolism; Subcellular localization as predicted by Psort 2.0: Cytoplasmic. | 0.824 |
| ilvA | metH | PANA_3825 | PANA_0241 | IlvA; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | MetH; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.888 |
| ilvA | metL | PANA_3825 | PANA_3848 | IlvA; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | MetL; Bifunctional aspartokinase/homoserine dehydrogenase II; Similar to Pantoea sp. At-9b, aspartate kinase (NCBI: ZP_05730334.1); COG: Amino acid transport and metabolism; Subcellular localization as predicted by Psort 2.0: Inner Membrane; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.718 |
| ilvA | sdaA | PANA_3825 | PANA_2142 | IlvA; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | SdaA; L-serine dehydratase 1; Similar to Pantoea sp. At-9b, L-serine dehydratase 1 (NCBI: ZP_05728602.1); COG: Amino acid transport and metabolism; Subcellular localization as predicted by Psort 2.0: Unknown; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.920 |
| ilvA | tdcB | PANA_3825 | PANA_0884 | IlvA; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | TdcB; Threonine dehydratase catabolic; Similar to Rhizobium leguminosarum bv. trifolii WSM2304, Pyridoxal-5'-phosphate-dependent protein beta subunit (NCBI: YP_002278414.1); COG: Amino acid transport and metabolism; Subcellular localization as predicted by Psort 2.0: Unknown. | 0.917 |
| ilvA | tdcB-2 | PANA_3825 | PANA_3471 | IlvA; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | TdcB; Threonine dehydratase catabolic; Similar to Citrobacter koseri ATCC BAA-895, threonine dehydratase (NCBI: YP_001456008.1); COG: Amino acid transport and metabolism; Subcellular localization as predicted by Psort 2.0: Unknown. | 0.915 |
| ilvA | thrA | PANA_3825 | PANA_0655 | IlvA; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | ThrA; Bifunctional aspartokinase/homoserine dehydrogenase I; Similar to Pantoea sp. At-9b, aspartate kinase (NCBI: ZP_05729729.1); COG: Amino acid transport and metabolism; Subcellular localization as predicted by Psort 2.0: Unknown; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.718 |
| ilvA | trpB | PANA_3825 | PANA_2069 | IlvA; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | TrpB; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.927 |
| metA | ilvA | PANA_0232 | PANA_3825 | MetA; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family. | IlvA; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.818 |
| metA | metB | PANA_0232 | PANA_3849 | MetA; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family. | MetB; Cystathionine gamma-synthase; Similar to Pantoea sp. At-9b, O-succinylhomoserine (thiol)-lyase (NCBI: ZP_05730335.1); COG: Amino acid transport and metabolism; Subcellular localization as predicted by Psort 2.0: Cytoplasmic. | 0.976 |
| metA | metF | PANA_0232 | PANA_3847 | MetA; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family. | MetF; 5,10-methylenetetrahydrofolate reductase; Similar to Pantoea sp. At-9b, 5,10-methylenetetrahydrofolate reductase (NCBI: ZP_05730333.1); COG: Amino acid transport and metabolism; Subcellular localization as predicted by Psort 2.0: Unknown. | 0.885 |
| metA | metH | PANA_0232 | PANA_0241 | MetA; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family. | MetH; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.854 |
| metA | metL | PANA_0232 | PANA_3848 | MetA; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family. | MetL; Bifunctional aspartokinase/homoserine dehydrogenase II; Similar to Pantoea sp. At-9b, aspartate kinase (NCBI: ZP_05730334.1); COG: Amino acid transport and metabolism; Subcellular localization as predicted by Psort 2.0: Inner Membrane; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.966 |
| metA | sdaA | PANA_0232 | PANA_2142 | MetA; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family. | SdaA; L-serine dehydratase 1; Similar to Pantoea sp. At-9b, L-serine dehydratase 1 (NCBI: ZP_05728602.1); COG: Amino acid transport and metabolism; Subcellular localization as predicted by Psort 2.0: Unknown; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.821 |
| metA | tdcB | PANA_0232 | PANA_0884 | MetA; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family. | TdcB; Threonine dehydratase catabolic; Similar to Rhizobium leguminosarum bv. trifolii WSM2304, Pyridoxal-5'-phosphate-dependent protein beta subunit (NCBI: YP_002278414.1); COG: Amino acid transport and metabolism; Subcellular localization as predicted by Psort 2.0: Unknown. | 0.818 |
| metA | tdcB-2 | PANA_0232 | PANA_3471 | MetA; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family. | TdcB; Threonine dehydratase catabolic; Similar to Citrobacter koseri ATCC BAA-895, threonine dehydratase (NCBI: YP_001456008.1); COG: Amino acid transport and metabolism; Subcellular localization as predicted by Psort 2.0: Unknown. | 0.818 |
| metA | thrA | PANA_0232 | PANA_0655 | MetA; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family. | ThrA; Bifunctional aspartokinase/homoserine dehydrogenase I; Similar to Pantoea sp. At-9b, aspartate kinase (NCBI: ZP_05729729.1); COG: Amino acid transport and metabolism; Subcellular localization as predicted by Psort 2.0: Unknown; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.970 |
| metA | trpB | PANA_0232 | PANA_2069 | MetA; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family. | TrpB; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.815 |
| metB | ilvA | PANA_3849 | PANA_3825 | MetB; Cystathionine gamma-synthase; Similar to Pantoea sp. At-9b, O-succinylhomoserine (thiol)-lyase (NCBI: ZP_05730335.1); COG: Amino acid transport and metabolism; Subcellular localization as predicted by Psort 2.0: Cytoplasmic. | IlvA; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.824 |
page 1 of 5