Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rnhBRnhB; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (215 aa)    
Predicted Functional Partners:
lpxB
LpxB; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
  
  
 0.973
lpxA
LpxA; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
  
  
 0.962
dnaE
DnaE; DNA polymerase III alpha subunit; Similar to Pantoea sp. At-9b, DNA polymerase III, alpha subunit (NCBI: ZP_05731577.1); COG: DNA replication, recombination and repair; Subcellular localization as predicted by Psort 2.0: Cytoplasmic.
  
  
 0.895
polA
PolA; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
 
 0.880
lepB
LepB; Signal peptidase I; Similar to Pantoea sp. At-9b, signal peptidase I (NCBI: ZP_05727802.1); COG: Intracellular trafficking, secretion, and vesicular transport; Subcellular localization as predicted by Psort 2.0: Inner Membrane; Belongs to the peptidase S26 family.
  
  
 0.836
rnhA
RnhA; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
   
 
 0.833
queH
Hypothetical Protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
 
      0.827
dnaN
DnaN; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for [...]
   
 
 0.826
rpoC
RpoC; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.769
recQ
RecQ; ATP-dependent DNA helicase RecQ; Similar to Pantoea sp. At-9b, ATP-dependent DNA helicase RecQ (NCBI: ZP_05730688.1); COG: DNA replication, recombination and repair; Subcellular localization as predicted by Psort 2.0: Cytoplasmic.
  
 
 0.754
Your Current Organism:
Pantoea ananatis
NCBI taxonomy Id: 706191
Other names: P. ananatis LMG 20103, Pantoea ananatis LMG 20103, Pantoea ananatis str. LMG 20103, Pantoea ananatis strain LMG 20103
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