Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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accAAccA; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (318 aa)    
Predicted Functional Partners:
accD
AccD; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
 0.999
accB
AccB; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 
 0.996
accC
AccC; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 
 0.996
fabD
FabD; Malonyl CoA-acyl carrier protein transacylase; Similar to Pantoea sp. At-9b, malonyl CoA-acyl carrier protein transacylase (NCBI: ZP_05728384.1); COG: Lipid transport and metabolism; Subcellular localization as predicted by Psort 2.0: Cytoplasmic.
 
 
 0.983
fabH
FabH; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
 
 
 0.976
pta
Pta; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
    
  0.906
acs
Acs; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
    
  0.905
aceF
AceF; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
     
 0.902
mmsA
MmsA; Methylmalonate-semialdehyde dehydrogenase [acylating]; Similar to Pantoea sp. At-9b, methylmalonate-semialdehyde dehydrogenase (NCBI: ZP_05731807.1); COG: Energy production and conversion; Subcellular localization as predicted by Psort 2.0: Cytoplasmic.
     
 0.902
adhE
AdhE; Aldehyde-alcohol dehydrogenase [Includes: Alcohol dehydrogenase]; Similar to Pantoea sp. At-9b, iron-containing alcohol dehydrogenase (NCBI: ZP_05729406.1); COG: Energy production and conversion; Subcellular localization as predicted by Psort 2.0: Unknown; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
     
 0.901
Your Current Organism:
Pantoea ananatis
NCBI taxonomy Id: 706191
Other names: P. ananatis LMG 20103, Pantoea ananatis LMG 20103, Pantoea ananatis str. LMG 20103, Pantoea ananatis strain LMG 20103
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