Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
aptApt; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (204 aa)    
Predicted Functional Partners:
purH
PurH; Bifunctional purine biosynthesis protein PurH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase]; Similar to Pantoea sp. At-9b, phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (NCBI: ZP_05732296.1); COG: Nucleotide transport and metabolism; Subcellular localization as predicted by Psort 2.0: Unknown.
 
 0.961
purB
PurB; Adenylosuccinate lyase; Similar to Pantoea sp. At-9b, adenylosuccinate lyase (NCBI: ZP_05728421.1); COG: Nucleotide transport and metabolism; Subcellular localization as predicted by Psort 2.0: Unknown.
  
 0.955
adk
Adk; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
  
 0.934
surE
SurE; Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs.
    
 0.924
deoD
DeoD; Purine nucleoside phosphorylase; Similar to Erwinia pyrifoliae Ep1/96, Purine nucleoside phosphorylase deoD-type (NCBI: YP_002647696.1); COG: Nucleotide transport and metabolism; Subcellular localization as predicted by Psort 2.0: Cytoplasmic.
    
 0.916
amn
Amn; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.
   
 0.915
ushA
UshA; Protein UshA precursor [Includes: UDP-sugar hydrolase]; Similar to Pantoea sp. At-9b, 5'-Nucleotidase domain protein (NCBI: ZP_05727532.1); COG: Nucleotide transport and metabolism; Subcellular localization as predicted by Psort 2.0: Periplasmic; Belongs to the 5'-nucleotidase family.
    
 0.911
ygdH
YgdH; Decarboxylase Family Protei; Similar to Pantoea sp. At-9b, conserved hypothetical protein (NCBI: ZP_05732169.1); COG: General function prediction only; Subcellular localization as predicted by Psort 2.0: Unknown.
    
 0.907
yfiH
YfiH; Hypothetical UPF0124 protein YfiH; Similar to Pantoea sp. At-9b, protein of unknown function DUF152 (NCBI: ZP_05731650.1); COG: Unknown Function; Subcellular localization as predicted by Psort 2.0: Unknown; Belongs to the multicopper oxidase YfiH/RL5 family.
    
  0.905
yfiH-2
YfiH; Hypothetical UPF0124 protein; Similar to Pantoea sp. At-9b, protein of unknown function DUF152 (NCBI: ZP_05730538.1); COG: Unknown Function; Subcellular localization as predicted by Psort 2.0: Unknown.
    
  0.905
Your Current Organism:
Pantoea ananatis
NCBI taxonomy Id: 706191
Other names: P. ananatis LMG 20103, Pantoea ananatis LMG 20103, Pantoea ananatis str. LMG 20103, Pantoea ananatis strain LMG 20103
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