STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PANA_1908Hypothetical Protein; RNA polymerase, sigma-24 subunit, ECF family; Similar to Dickeya dadantii Ech586, RNA polymerase, sigma-24 subunit, ECF subfamily (NCBI: YP_003333627.1); COG: Transcription; Subcellular localization as predicted by Psort 2.0: Unknown; Belongs to the sigma-70 factor family. ECF subfamily. (186 aa)    
Predicted Functional Partners:
PANA_1907
Hypothetical Protein; Similar to Dickeya dadantii Ech586, hypothetical protein Dd586_2066 (NCBI: YP_003333626.1); COG: Unknown Function; Subcellular localization as predicted by Psort 2.0: Unknown.
 
     0.950
rseA
RseA; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sig [...]
  
 
 0.827
PANA_1603
Hypothetical Protein; Transmembrane Transcriptional Regulator; Similar to Pectobacterium carotovorum subsp. carotovorum PC1, putative transmembrane anti-sigma factor (NCBI: YP_003017846.1); COG: Transcription; Subcellular localization as predicted by Psort 2.0: Unknown.
  
 
 0.648
rpoC
RpoC; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.610
rpoB
RpoB; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.585
cheR
CheR; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.
    
   0.509
rpoA
RpoA; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.491
rpoZ
RpoZ; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 
 0.491
yieL
YieL; Protein YieL; Similar to Klebsiella pneumoniae subsp. pneumoniae MGH 78578, putative xylanase (NCBI: YP_001337777.1); COG: Inorganic ion transport and metabolism; Subcellular localization as predicted by Psort 2.0: Unknown.
  
    0.475
iutA
IutA; Ferric aerobactin receptor precursor; Similar to Pectobacterium atrosepticum SCRI1043, TonB-dependent ferric aerobactin receptor (NCBI: YP_048985.1); COG: Inorganic ion transport and metabolism; Subcellular localization as predicted by Psort 2.0: Outer Membrane.
  
  
 0.445
Your Current Organism:
Pantoea ananatis
NCBI taxonomy Id: 706191
Other names: P. ananatis LMG 20103, Pantoea ananatis LMG 20103, Pantoea ananatis str. LMG 20103, Pantoea ananatis strain LMG 20103
Server load: low (34%) [HD]