Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ldhALdhA; Hypothetical Protein LdhA; Similar to Pantoea sp. At-9b, D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding (NCBI: ZP_05729565.1); COG: Energy production and conversion; Subcellular localization as predicted by Psort 2.0: Cytoplasmic. (340 aa)    
Predicted Functional Partners:
maeB
MaeB; NADP-dependent malic enzyme; Similar to Pantoea sp. At-9b, Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)), Phosphate acetyltransferase (NCBI: ZP_05727679.1); COG: Energy production and conversion; Subcellular localization as predicted by Psort 2.0: Unknown.
   
 0.929
dld
Dld; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family.
   
 0.927
ppsA
PpsA; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
 
  
 0.925
lldD
LldD; Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain; Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
  
 
 0.923
lldD-2
LldD; L-lactate dehydrogenase; Similar to Klebsiella pneumoniae subsp. pneumoniae MGH 78578, L-lactate dehydrogenase (NCBI: YP_001335801.1); COG: Energy production and conversion; Subcellular localization as predicted by Psort 2.0: Unknown.
  
 
 0.923
pykA
PykA; Pyruvate kinase II; Similar to Pantoea sp. At-9b, pyruvate kinase (NCBI: ZP_05728670.1); COG: Signal transduction mechanisms; Subcellular localization as predicted by Psort 2.0: Unknown.
  
 0.922
pykF
PykF; Pyruvate kinase I; Similar to Pantoea sp. At-9b, pyruvate kinase (NCBI: ZP_05728578.1); COG: Carbohydrate transport and metabolism; Subcellular localization as predicted by Psort 2.0: Unknown.
  
 0.921
pflB
PflB; Formate acetyltransferase 1; Similar to Pantoea sp. At-9b, formate acetyltransferase (NCBI: ZP_05728880.1); COG: Energy production and conversion; Subcellular localization as predicted by Psort 2.0: Cytoplasmic.
     
 0.914
aceE
AceE; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
     
 0.912
poxB
PoxB; Pyruvate dehydrogenase [cytochrome]; Similar to Pantoea sp. At-9b, thiamine pyrophosphate protein TPP binding domain protein (NCBI: ZP_05728862.1); COG: Amino acid transport and metabolism; Subcellular localization as predicted by Psort 2.0: Inner Membrane; Belongs to the TPP enzyme family.
  
 
 0.905
Your Current Organism:
Pantoea ananatis
NCBI taxonomy Id: 706191
Other names: P. ananatis LMG 20103, Pantoea ananatis LMG 20103, Pantoea ananatis str. LMG 20103, Pantoea ananatis strain LMG 20103
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