Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ydjAYdjA; Protein YdjA; Similar to Pantoea sp. At-9b, nitroreductase (NCBI: ZP_05729423.1); COG: Energy production and conversion; Subcellular localization as predicted by Psort 2.0: Unknown. (183 aa)    
Predicted Functional Partners:
topB
TopB; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally [...]
 
   
 0.636
yadH
YadH; Inner membrane transport permease YadH; Similar to Pantoea sp. At-9b, ABC-2 type transporter (NCBI: ZP_05729841.1); COG: Defense mechanisms; Subcellular localization as predicted by Psort 2.0: Inner Membrane.
  
  
 0.619
sppA
SppA; Protease IV; Similar to Pantoea sp. At-9b, signal peptide peptidase SppA, 67K type (NCBI: ZP_05729424.1); COG: Posttranslational modification, protein turnover, chaperones; Subcellular localization as predicted by Psort 2.0: Inner Membrane.
     
 0.613
birA
BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
  
    0.565
ycaO
YcaO; Cytoplasmic UPF0142 Family Protein; Similar to Pantoea sp. At-9b, protein of unknown function DUF181 (NCBI: ZP_05728882.1); COG: Unknown Function; Subcellular localization as predicted by Psort 2.0: Unknown.
  
  
 0.559
ynjH
YnjH; Periplasmic Protein YnjH; Similar to Pantoea sp. At-9b, protein of unknown function DUF1496 (NCBI: ZP_05729420.1); COG: Unknown Function; Subcellular localization as predicted by Psort 2.0: Unknown.
       0.553
tadA
TadA; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
  
  
 0.472
ansA
AnsA; L-asparaginase I; Similar to Pantoea sp. At-9b, L-asparaginase, type I (NCBI: ZP_05729425.1); COG: Amino acid transport and metabolism; Subcellular localization as predicted by Psort 2.0: Cytoplasmic.
       0.470
pncA
PncA; Pyrazinamidase/nicotinamidase; Similar to Pantoea sp. At-9b, Nicotinamidase (NCBI: ZP_05729426.1); COG: Secondary metabolites biosynthesis, transport and catabolism; Subcellular localization as predicted by Psort 2.0: Cytoplasmic.
  
  
 0.463
fadD
FadD; Long-chain-fatty-acid--CoA ligase; Similar to Pantoea sp. At-9b, AMP-dependent synthetase and ligase (NCBI: ZP_05728594.1); COG: Lipid transport and metabolism; Subcellular localization as predicted by Psort 2.0: Cytoplasmic.
 
 
   0.430
Your Current Organism:
Pantoea ananatis
NCBI taxonomy Id: 706191
Other names: P. ananatis LMG 20103, Pantoea ananatis LMG 20103, Pantoea ananatis str. LMG 20103, Pantoea ananatis strain LMG 20103
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