Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dsbBDsbB; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family. (196 aa)    
Predicted Functional Partners:
dsbA
DsbA; Thiol:disulfide interchange protein DsbA precursor; Similar to Pantoea sp. At-9b, DSBA oxidoreductase (NCBI: ZP_05730425.1); COG: Posttranslational modification, protein turnover, chaperones; Subcellular localization as predicted by Psort 2.0: Periplasmic.
 
 
 0.970
fadR
FadR; Multifunctional regulator of fatty acid metabolism.
 
  
 0.852
guaB
GuaB; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 
 0.832
pyrD
PyrD; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
     
 0.823
dsbC
DsbC; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.
 
 
 0.791
yrbK
YrbK; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family.
  
   
 0.773
carB
Carbamoyl-phosphate synthase large chain; Similar to Pantoea sp. At-9b, carbamoyl-phosphate synthase, large subunit (NCBI: ZP_05729750.1); COG: Amino acid transport and metabolism; Subcellular localization as predicted by Psort 2.0: Cytoplasmic; Belongs to the CarB family.
      
 0.753
proQ
ProQ; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism. Belongs to the ProQ family.
  
     0.743
yjgD
YjgD; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
  
     0.739
slyX
SlyX; Protein SlyX; Similar to Pantoea sp. At-9b, SlyX family protein (NCBI: ZP_05731059.1); COG: General function prediction only; Subcellular localization as predicted by Psort 2.0: Unknown; Belongs to the SlyX family.
  
   
 0.723
Your Current Organism:
Pantoea ananatis
NCBI taxonomy Id: 706191
Other names: P. ananatis LMG 20103, Pantoea ananatis LMG 20103, Pantoea ananatis str. LMG 20103, Pantoea ananatis strain LMG 20103
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.