STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
minCMinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. (232 aa)    
Predicted Functional Partners:
minD
MinD; Septum site-determining protein MinD; Similar to Pantoea sp. At-9b, septum site-determining protein MinD (NCBI: ZP_05728591.1); COG: Cell division and chromosome partitioning; Subcellular localization as predicted by Psort 2.0: Unknown.
 
 
 0.998
minE
MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
 
  
 0.929
mreC
MreC; Rod shape-determining protein MreC; Similar to Pantoea sp. At-9b, rod shape-determining protein MreC (NCBI: ZP_05732146.1); COG: Cell wall/membrane/envelope biogenesis; Subcellular localization as predicted by Psort 2.0: Unknown.
  
  
 0.859
mreD
MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family.
  
  
 0.846
ftsZ
FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
   
 
 0.812
ycgL
YcgL; Protein YcgL; Similar to Pantoea sp. At-9b, protein of unknown function DUF709 (NCBI: ZP_05728589.1); COG: Unknown Function; Subcellular localization as predicted by Psort 2.0: Unknown.
  
  
 0.624
ffh
Ffh; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components; Belongs to the GTP-binding S [...]
  
  
 0.590
tgt
Tgt; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociati [...]
  
    0.499
yhjQ
YhjQ; Cellulose Biosynthesis Protein; Similar to Pantoea sp. At-9b, cellulose synthase operon protein YhjQ (NCBI: ZP_05732368.1); COG: DNA replication, recombination and repair; Subcellular localization as predicted by Psort 2.0: Unknown.
  
  
 0.470
cmk
Cmk; Cytidylate kinase; Similar to Pantoea sp. At-9b, cytidylate kinase (NCBI: ZP_05728885.1); COG: Nucleotide transport and metabolism; Subcellular localization as predicted by Psort 2.0: Cytoplasmic.
   
    0.465
Your Current Organism:
Pantoea ananatis
NCBI taxonomy Id: 706191
Other names: P. ananatis LMG 20103, Pantoea ananatis LMG 20103, Pantoea ananatis str. LMG 20103, Pantoea ananatis strain LMG 20103
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