| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cmk | ffh | PANA_1352 | PANA_3024 | Cmk; Cytidylate kinase; Similar to Pantoea sp. At-9b, cytidylate kinase (NCBI: ZP_05728885.1); COG: Nucleotide transport and metabolism; Subcellular localization as predicted by Psort 2.0: Cytoplasmic. | Ffh; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components; Belongs to the GTP-binding S [...] | 0.788 |
| cmk | minC | PANA_1352 | PANA_2129 | Cmk; Cytidylate kinase; Similar to Pantoea sp. At-9b, cytidylate kinase (NCBI: ZP_05728885.1); COG: Nucleotide transport and metabolism; Subcellular localization as predicted by Psort 2.0: Cytoplasmic. | MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | 0.465 |
| cmk | mreC | PANA_1352 | PANA_3565 | Cmk; Cytidylate kinase; Similar to Pantoea sp. At-9b, cytidylate kinase (NCBI: ZP_05728885.1); COG: Nucleotide transport and metabolism; Subcellular localization as predicted by Psort 2.0: Cytoplasmic. | MreC; Rod shape-determining protein MreC; Similar to Pantoea sp. At-9b, rod shape-determining protein MreC (NCBI: ZP_05732146.1); COG: Cell wall/membrane/envelope biogenesis; Subcellular localization as predicted by Psort 2.0: Unknown. | 0.461 |
| cmk | mreD | PANA_1352 | PANA_3564 | Cmk; Cytidylate kinase; Similar to Pantoea sp. At-9b, cytidylate kinase (NCBI: ZP_05728885.1); COG: Nucleotide transport and metabolism; Subcellular localization as predicted by Psort 2.0: Cytoplasmic. | MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family. | 0.415 |
| ffh | cmk | PANA_3024 | PANA_1352 | Ffh; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components; Belongs to the GTP-binding S [...] | Cmk; Cytidylate kinase; Similar to Pantoea sp. At-9b, cytidylate kinase (NCBI: ZP_05728885.1); COG: Nucleotide transport and metabolism; Subcellular localization as predicted by Psort 2.0: Cytoplasmic. | 0.788 |
| ffh | ftsZ | PANA_3024 | PANA_0724 | Ffh; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components; Belongs to the GTP-binding S [...] | FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.590 |
| ffh | minC | PANA_3024 | PANA_2129 | Ffh; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components; Belongs to the GTP-binding S [...] | MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | 0.590 |
| ftsZ | ffh | PANA_0724 | PANA_3024 | FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | Ffh; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components; Belongs to the GTP-binding S [...] | 0.590 |
| ftsZ | minC | PANA_0724 | PANA_2129 | FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | 0.812 |
| ftsZ | mreC | PANA_0724 | PANA_3565 | FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | MreC; Rod shape-determining protein MreC; Similar to Pantoea sp. At-9b, rod shape-determining protein MreC (NCBI: ZP_05732146.1); COG: Cell wall/membrane/envelope biogenesis; Subcellular localization as predicted by Psort 2.0: Unknown. | 0.601 |
| ftsZ | yhjQ | PANA_0724 | PANA_0127 | FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | YhjQ; Cellulose Biosynthesis Protein; Similar to Pantoea sp. At-9b, cellulose synthase operon protein YhjQ (NCBI: ZP_05732368.1); COG: DNA replication, recombination and repair; Subcellular localization as predicted by Psort 2.0: Unknown. | 0.490 |
| minC | cmk | PANA_2129 | PANA_1352 | MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | Cmk; Cytidylate kinase; Similar to Pantoea sp. At-9b, cytidylate kinase (NCBI: ZP_05728885.1); COG: Nucleotide transport and metabolism; Subcellular localization as predicted by Psort 2.0: Cytoplasmic. | 0.465 |
| minC | ffh | PANA_2129 | PANA_3024 | MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | Ffh; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components; Belongs to the GTP-binding S [...] | 0.590 |
| minC | ftsZ | PANA_2129 | PANA_0724 | MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.812 |
| minC | minD | PANA_2129 | PANA_2130 | MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | MinD; Septum site-determining protein MinD; Similar to Pantoea sp. At-9b, septum site-determining protein MinD (NCBI: ZP_05728591.1); COG: Cell division and chromosome partitioning; Subcellular localization as predicted by Psort 2.0: Unknown. | 0.998 |
| minC | minE | PANA_2129 | PANA_2131 | MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. | 0.929 |
| minC | mreC | PANA_2129 | PANA_3565 | MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | MreC; Rod shape-determining protein MreC; Similar to Pantoea sp. At-9b, rod shape-determining protein MreC (NCBI: ZP_05732146.1); COG: Cell wall/membrane/envelope biogenesis; Subcellular localization as predicted by Psort 2.0: Unknown. | 0.859 |
| minC | mreD | PANA_2129 | PANA_3564 | MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family. | 0.846 |
| minC | tgt | PANA_2129 | PANA_0963 | MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | Tgt; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociati [...] | 0.499 |
| minC | ycgL | PANA_2129 | PANA_2128 | MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | YcgL; Protein YcgL; Similar to Pantoea sp. At-9b, protein of unknown function DUF709 (NCBI: ZP_05728589.1); COG: Unknown Function; Subcellular localization as predicted by Psort 2.0: Unknown. | 0.624 |