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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aglBAglB; 6-phospho-alpha-glucosidase; Similar to Klebsiella pneumoniae subsp. pneumoniae MGH 78578, glycoside hydrolase family protein 4 (NCBI: YP_001337735.1); COG: Carbohydrate transport and metabolism; Subcellular localization as predicted by Psort 2.0: Unknown. (440 aa)    
Predicted Functional Partners:
aglA
AglA; PTS system alpha-glucoside-specific EIICB component [Includes: Alpha- glucoside permease IIC component]; Similar to Klebsiella pneumoniae 342, PTS system, alpha-glucoside-specific EIICB component (NCBI: YP_002235899.1); COG: Carbohydrate transport and metabolism; Subcellular localization as predicted by Psort 2.0: Inner Membrane.
 
 
 0.995
malX
MalX; PTS system maltose- and glucose-specific EIICB component [Includes: Maltose and glucose permease IIC component]; Similar to Pantoea sp. At-9b, PTS system, glucose-like IIB subunint (NCBI: ZP_05729286.1); COG: Carbohydrate transport and metabolism; Subcellular localization as predicted by Psort 2.0: Inner Membrane.
 
 
 0.944
crr
Crr; Glucose-specific phosphotransferase enzyme IIA component; Similar to Erwinia tasmaniensis Et1/99, glucose-specific PTS system component (NCBI: YP_001907040.1); COG: Carbohydrate transport and metabolism; Subcellular localization as predicted by Psort 2.0: Cytoplasmic.
 
  
 0.919
otsA
OtsA; Alpha,alpha-trehalose-phosphate synthase [UDP-forming]; Similar to Pantoea sp. At-9b, Alpha,alpha-trehalose-phosphate synthase (UDP-forming) (NCBI: ZP_05730825.1); COG: Carbohydrate transport and metabolism; Subcellular localization as predicted by Psort 2.0: Cytoplasmic.
    
  0.901
otsA-2
OtsA; Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D- glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose- 6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor; Belongs to the glycosyltransferase 20 family.
    
  0.901
treA
TreA; Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system; Belongs to the glycosyl hydrolase 37 family.
     
  0.900
otsB
OtsB; Removes the phosphate from trehalose 6-phosphate to produce free trehalose.
     
  0.900
treF
TreF; Hydrolyzes trehalose to glucose. Could be involved, in cells returning to low osmolarity conditions, in the utilization of the accumulated cytoplasmic trehalose, which was synthesized in response to high osmolarity.
     
  0.900
yidP
YidP; Transcriptional Regulator GntR Family; Similar to Klebsiella pneumoniae subsp. rhinoscleromatis ATCC 13884, GntR family transcriptional regulator (NCBI: ZP_06013691.1); COG: Transcription; Subcellular localization as predicted by Psort 2.0: Unknown.
 
     0.750
scrA-2
ScrA; PTS system sucrose-specific EIIBC component; Similar to Pantoea sp. At-9b, PTS system, sucrose-specific IIBC subunit (NCBI: ZP_05731864.1); COG: Carbohydrate transport and metabolism; Subcellular localization as predicted by Psort 2.0: Inner Membrane.
 
  
 0.730
Your Current Organism:
Pantoea ananatis
NCBI taxonomy Id: 706191
Other names: P. ananatis LMG 20103, Pantoea ananatis LMG 20103, Pantoea ananatis str. LMG 20103, Pantoea ananatis strain LMG 20103
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