STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
icc-2Icc; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. (275 aa)    
Predicted Functional Partners:
cyaA
CyaA; Adenylate cyclase; Similar to Pantoea sp. At-9b, putative adenylate cyclase (NCBI: ZP_05730676.1); COG: Nucleotide transport and metabolism; Subcellular localization as predicted by Psort 2.0: Cytoplasmic; Belongs to the adenylyl cyclase class-1 family.
  
  
 0.959
icc
Icc; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.
  
  
 
0.925
mazG
MazG; Protein MazG; Similar to Pantoea sp. At-9b, MazG family protein (NCBI: ZP_05731704.1); COG: Nucleotide transport and metabolism; Subcellular localization as predicted by Psort 2.0: Unknown.
  
  
  0.918
ushA
UshA; Protein UshA precursor [Includes: UDP-sugar hydrolase]; Similar to Pantoea sp. At-9b, 5'-Nucleotidase domain protein (NCBI: ZP_05727532.1); COG: Nucleotide transport and metabolism; Subcellular localization as predicted by Psort 2.0: Periplasmic; Belongs to the 5'-nucleotidase family.
   
 
 0.907
ygdH
YgdH; Decarboxylase Family Protei; Similar to Pantoea sp. At-9b, conserved hypothetical protein (NCBI: ZP_05732169.1); COG: General function prediction only; Subcellular localization as predicted by Psort 2.0: Unknown.
    
  0.902
yqiA
YqiA; Esterase YqiA; Similar to Pantoea sp. At-9b, protein of unknown function UPF0227 (NCBI: ZP_05730444.1); COG: General function prediction only; Subcellular localization as predicted by Psort 2.0: Unknown.
 
  
 0.902
apt
Apt; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
    
  0.901
adk
Adk; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
     
 0.901
yjjG
YjjG; 5'-nucleotidase YjjG; Similar to Pantoea sp. At-9b, HAD-superfamily hydrolase, subfamily IA, variant 1 (NCBI: ZP_05730074.1); COG: Nucleotide transport and metabolism; Subcellular localization as predicted by Psort 2.0: Unknown.
    
  0.900
purB
PurB; Adenylosuccinate lyase; Similar to Pantoea sp. At-9b, adenylosuccinate lyase (NCBI: ZP_05728421.1); COG: Nucleotide transport and metabolism; Subcellular localization as predicted by Psort 2.0: Unknown.
     
  0.900
Your Current Organism:
Pantoea ananatis
NCBI taxonomy Id: 706191
Other names: P. ananatis LMG 20103, Pantoea ananatis LMG 20103, Pantoea ananatis str. LMG 20103, Pantoea ananatis strain LMG 20103
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