node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EFW23584.1 | EFW25056.1 | HMPREF9430_01926 | HMPREF9430_00208 | Sua5/YciO/YrdC/YwlC family protein; KEGG: rcm:A1E_05435 6.9e-18 bifunctional N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase/tRNA (m7G46) methyltransferase K07566; Psort location: Cytoplasmic, score: 7.50; Belongs to the SUA5 family. | Hydrolase, P-loop family. | 0.443 |
EFW23584.1 | ksgA | HMPREF9430_01926 | HMPREF9430_00457 | Sua5/YciO/YrdC/YwlC family protein; KEGG: rcm:A1E_05435 6.9e-18 bifunctional N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase/tRNA (m7G46) methyltransferase K07566; Psort location: Cytoplasmic, score: 7.50; Belongs to the SUA5 family. | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.583 |
EFW23584.1 | polA | HMPREF9430_01926 | HMPREF9430_00753 | Sua5/YciO/YrdC/YwlC family protein; KEGG: rcm:A1E_05435 6.9e-18 bifunctional N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase/tRNA (m7G46) methyltransferase K07566; Psort location: Cytoplasmic, score: 7.50; Belongs to the SUA5 family. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.500 |
EFW23584.1 | tsaD | HMPREF9430_01926 | HMPREF9430_00211 | Sua5/YciO/YrdC/YwlC family protein; KEGG: rcm:A1E_05435 6.9e-18 bifunctional N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase/tRNA (m7G46) methyltransferase K07566; Psort location: Cytoplasmic, score: 7.50; Belongs to the SUA5 family. | Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.774 |
EFW23584.1 | yeaZ | HMPREF9430_01926 | HMPREF9430_00209 | Sua5/YciO/YrdC/YwlC family protein; KEGG: rcm:A1E_05435 6.9e-18 bifunctional N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase/tRNA (m7G46) methyltransferase K07566; Psort location: Cytoplasmic, score: 7.50; Belongs to the SUA5 family. | Universal bacterial protein YeaZ. | 0.522 |
EFW25056.1 | EFW23584.1 | HMPREF9430_00208 | HMPREF9430_01926 | Hydrolase, P-loop family. | Sua5/YciO/YrdC/YwlC family protein; KEGG: rcm:A1E_05435 6.9e-18 bifunctional N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase/tRNA (m7G46) methyltransferase K07566; Psort location: Cytoplasmic, score: 7.50; Belongs to the SUA5 family. | 0.443 |
EFW25056.1 | pheT | HMPREF9430_00208 | HMPREF9430_01426 | Hydrolase, P-loop family. | KEGG: gwc:GWCH70_2648 1.4e-143 phenylalanyl-tRNA synthetase, beta subunit K01890; Psort location: Cytoplasmic, score: 9.97. | 0.404 |
EFW25056.1 | polA | HMPREF9430_00208 | HMPREF9430_00753 | Hydrolase, P-loop family. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.416 |
EFW25056.1 | rex | HMPREF9430_00208 | HMPREF9430_00212 | Hydrolase, P-loop family. | CoA binding domain protein; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. | 0.691 |
EFW25056.1 | rimI | HMPREF9430_00208 | HMPREF9430_00210 | Hydrolase, P-loop family. | Ribosomal-protein-alanine acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18. | 0.913 |
EFW25056.1 | tsaD | HMPREF9430_00208 | HMPREF9430_00211 | Hydrolase, P-loop family. | Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.998 |
EFW25056.1 | yeaZ | HMPREF9430_00208 | HMPREF9430_00209 | Hydrolase, P-loop family. | Universal bacterial protein YeaZ. | 0.998 |
gpsA | polA | HMPREF9430_00980 | HMPREF9430_00753 | KEGG: efa:EF1747 4.7e-74 gpsA; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase K00057; Psort location: Cytoplasmic, score: 7.50; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.591 |
gpsA | tsaD | HMPREF9430_00980 | HMPREF9430_00211 | KEGG: efa:EF1747 4.7e-74 gpsA; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase K00057; Psort location: Cytoplasmic, score: 7.50; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. | Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.681 |
ksgA | EFW23584.1 | HMPREF9430_00457 | HMPREF9430_01926 | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | Sua5/YciO/YrdC/YwlC family protein; KEGG: rcm:A1E_05435 6.9e-18 bifunctional N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase/tRNA (m7G46) methyltransferase K07566; Psort location: Cytoplasmic, score: 7.50; Belongs to the SUA5 family. | 0.583 |
ksgA | leuS | HMPREF9430_00457 | HMPREF9430_00970 | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | leucine--tRNA ligase; KEGG: afl:Aflv_0425 4.8e-294 leuS; leucyl-tRNA synthetase; K01869 leucyl-tRNA synthetase; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.532 |
ksgA | pheT | HMPREF9430_00457 | HMPREF9430_01426 | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | KEGG: gwc:GWCH70_2648 1.4e-143 phenylalanyl-tRNA synthetase, beta subunit K01890; Psort location: Cytoplasmic, score: 9.97. | 0.625 |
ksgA | polA | HMPREF9430_00457 | HMPREF9430_00753 | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.643 |
ksgA | tsaD | HMPREF9430_00457 | HMPREF9430_00211 | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.652 |
leuS | ksgA | HMPREF9430_00970 | HMPREF9430_00457 | leucine--tRNA ligase; KEGG: afl:Aflv_0425 4.8e-294 leuS; leucyl-tRNA synthetase; K01869 leucyl-tRNA synthetase; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-I aminoacyl-tRNA synthetase family. | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.532 |