node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EFW23788.1 | EFW24161.1 | HMPREF9430_01593 | HMPREF9430_01251 | 5'-nucleotidase, C-terminal domain protein; KEGG: fno:Fnod_0639 1.8e-40 bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; K11751 5'-nucleotidase / UDP-sugar diphosphatase; Psort location: Cellwall, score: 8.97; Belongs to the 5'-nucleotidase family. | Glycosyl hydrolase family 25; KEGG: lsl:LSL_0805 1.9e-17 phage lysin K01185; Psort location: Cellwall, score: 8.97. | 0.446 |
EFW23788.1 | EFW24451.1 | HMPREF9430_01593 | HMPREF9430_01008 | 5'-nucleotidase, C-terminal domain protein; KEGG: fno:Fnod_0639 1.8e-40 bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; K11751 5'-nucleotidase / UDP-sugar diphosphatase; Psort location: Cellwall, score: 8.97; Belongs to the 5'-nucleotidase family. | CBS domain protein; KEGG: sgo:SGO_1625 3.0e-40 acetoin utilization putative/CBS domain-containing protein K04767; Psort location: Cytoplasmic, score: 7.50. | 0.915 |
EFW23788.1 | EFW25237.1 | HMPREF9430_01593 | HMPREF9430_00007 | 5'-nucleotidase, C-terminal domain protein; KEGG: fno:Fnod_0639 1.8e-40 bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; K11751 5'-nucleotidase / UDP-sugar diphosphatase; Psort location: Cellwall, score: 8.97; Belongs to the 5'-nucleotidase family. | 5'-nucleotidase, C-terminal domain protein; KEGG: bca:BCE_3724 4.5e-101 2,3-cyclic-nucleotide 2-phosphodiesterase, putative K01119; Psort location: Cellwall, score: 8.97; Belongs to the 5'-nucleotidase family. | 0.992 |
EFW23788.1 | EFW25353.1 | HMPREF9430_01593 | HMPREF9430_00123 | 5'-nucleotidase, C-terminal domain protein; KEGG: fno:Fnod_0639 1.8e-40 bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; K11751 5'-nucleotidase / UDP-sugar diphosphatase; Psort location: Cellwall, score: 8.97; Belongs to the 5'-nucleotidase family. | AICARFT/IMPCHase bienzyme; KEGG: bfs:BF2688 5.2e-155 5-aminoimidazole-4-carboxamide ribonucleotide transformylase K01492; Psort location: Cytoplasmic, score: 7.50. | 0.905 |
EFW23788.1 | guaA | HMPREF9430_01593 | HMPREF9430_01841 | 5'-nucleotidase, C-terminal domain protein; KEGG: fno:Fnod_0639 1.8e-40 bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; K11751 5'-nucleotidase / UDP-sugar diphosphatase; Psort location: Cellwall, score: 8.97; Belongs to the 5'-nucleotidase family. | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | 0.936 |
EFW23788.1 | hpt | HMPREF9430_01593 | HMPREF9430_01931 | 5'-nucleotidase, C-terminal domain protein; KEGG: fno:Fnod_0639 1.8e-40 bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; K11751 5'-nucleotidase / UDP-sugar diphosphatase; Psort location: Cellwall, score: 8.97; Belongs to the 5'-nucleotidase family. | KEGG: lla:L25115 3.1e-54 hpt; hypoxanthine phosphoribosyltransferase K00760; Psort location: Cytoplasmic, score: 9.97; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.902 |
EFW23788.1 | mgtE | HMPREF9430_01593 | HMPREF9430_00227 | 5'-nucleotidase, C-terminal domain protein; KEGG: fno:Fnod_0639 1.8e-40 bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; K11751 5'-nucleotidase / UDP-sugar diphosphatase; Psort location: Cellwall, score: 8.97; Belongs to the 5'-nucleotidase family. | Magnesium transporter; Acts as a magnesium transporter. | 0.496 |
EFW23788.1 | purA | HMPREF9430_01593 | HMPREF9430_01738 | 5'-nucleotidase, C-terminal domain protein; KEGG: fno:Fnod_0639 1.8e-40 bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; K11751 5'-nucleotidase / UDP-sugar diphosphatase; Psort location: Cellwall, score: 8.97; Belongs to the 5'-nucleotidase family. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.905 |
EFW23788.1 | rdgB | HMPREF9430_01593 | HMPREF9430_01645 | 5'-nucleotidase, C-terminal domain protein; KEGG: fno:Fnod_0639 1.8e-40 bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; K11751 5'-nucleotidase / UDP-sugar diphosphatase; Psort location: Cellwall, score: 8.97; Belongs to the 5'-nucleotidase family. | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.897 |
EFW24161.1 | EFW23788.1 | HMPREF9430_01251 | HMPREF9430_01593 | Glycosyl hydrolase family 25; KEGG: lsl:LSL_0805 1.9e-17 phage lysin K01185; Psort location: Cellwall, score: 8.97. | 5'-nucleotidase, C-terminal domain protein; KEGG: fno:Fnod_0639 1.8e-40 bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; K11751 5'-nucleotidase / UDP-sugar diphosphatase; Psort location: Cellwall, score: 8.97; Belongs to the 5'-nucleotidase family. | 0.446 |
EFW24161.1 | EFW24451.1 | HMPREF9430_01251 | HMPREF9430_01008 | Glycosyl hydrolase family 25; KEGG: lsl:LSL_0805 1.9e-17 phage lysin K01185; Psort location: Cellwall, score: 8.97. | CBS domain protein; KEGG: sgo:SGO_1625 3.0e-40 acetoin utilization putative/CBS domain-containing protein K04767; Psort location: Cytoplasmic, score: 7.50. | 0.498 |
EFW24161.1 | EFW25237.1 | HMPREF9430_01251 | HMPREF9430_00007 | Glycosyl hydrolase family 25; KEGG: lsl:LSL_0805 1.9e-17 phage lysin K01185; Psort location: Cellwall, score: 8.97. | 5'-nucleotidase, C-terminal domain protein; KEGG: bca:BCE_3724 4.5e-101 2,3-cyclic-nucleotide 2-phosphodiesterase, putative K01119; Psort location: Cellwall, score: 8.97; Belongs to the 5'-nucleotidase family. | 0.416 |
EFW24161.1 | EFW25353.1 | HMPREF9430_01251 | HMPREF9430_00123 | Glycosyl hydrolase family 25; KEGG: lsl:LSL_0805 1.9e-17 phage lysin K01185; Psort location: Cellwall, score: 8.97. | AICARFT/IMPCHase bienzyme; KEGG: bfs:BF2688 5.2e-155 5-aminoimidazole-4-carboxamide ribonucleotide transformylase K01492; Psort location: Cytoplasmic, score: 7.50. | 0.498 |
EFW24161.1 | guaA | HMPREF9430_01251 | HMPREF9430_01841 | Glycosyl hydrolase family 25; KEGG: lsl:LSL_0805 1.9e-17 phage lysin K01185; Psort location: Cellwall, score: 8.97. | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | 0.921 |
EFW24161.1 | hpt | HMPREF9430_01251 | HMPREF9430_01931 | Glycosyl hydrolase family 25; KEGG: lsl:LSL_0805 1.9e-17 phage lysin K01185; Psort location: Cellwall, score: 8.97. | KEGG: lla:L25115 3.1e-54 hpt; hypoxanthine phosphoribosyltransferase K00760; Psort location: Cytoplasmic, score: 9.97; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.523 |
EFW24161.1 | mgtE | HMPREF9430_01251 | HMPREF9430_00227 | Glycosyl hydrolase family 25; KEGG: lsl:LSL_0805 1.9e-17 phage lysin K01185; Psort location: Cellwall, score: 8.97. | Magnesium transporter; Acts as a magnesium transporter. | 0.463 |
EFW24161.1 | purA | HMPREF9430_01251 | HMPREF9430_01738 | Glycosyl hydrolase family 25; KEGG: lsl:LSL_0805 1.9e-17 phage lysin K01185; Psort location: Cellwall, score: 8.97. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.544 |
EFW24161.1 | rdgB | HMPREF9430_01251 | HMPREF9430_01645 | Glycosyl hydrolase family 25; KEGG: lsl:LSL_0805 1.9e-17 phage lysin K01185; Psort location: Cellwall, score: 8.97. | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.630 |
EFW24451.1 | EFW23788.1 | HMPREF9430_01008 | HMPREF9430_01593 | CBS domain protein; KEGG: sgo:SGO_1625 3.0e-40 acetoin utilization putative/CBS domain-containing protein K04767; Psort location: Cytoplasmic, score: 7.50. | 5'-nucleotidase, C-terminal domain protein; KEGG: fno:Fnod_0639 1.8e-40 bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; K11751 5'-nucleotidase / UDP-sugar diphosphatase; Psort location: Cellwall, score: 8.97; Belongs to the 5'-nucleotidase family. | 0.915 |
EFW24451.1 | EFW24161.1 | HMPREF9430_01008 | HMPREF9430_01251 | CBS domain protein; KEGG: sgo:SGO_1625 3.0e-40 acetoin utilization putative/CBS domain-containing protein K04767; Psort location: Cytoplasmic, score: 7.50. | Glycosyl hydrolase family 25; KEGG: lsl:LSL_0805 1.9e-17 phage lysin K01185; Psort location: Cellwall, score: 8.97. | 0.498 |