STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFW24932.1Nucleic acid-binding domain protein; Psort location: Cytoplasmic, score: 7.50. (95 aa)    
Predicted Functional Partners:
EFW24495.1
KEGG: gwc:GWCH70_2690 5.2e-194 DNA polymerase III, alpha subunit K02337; Psort location: Cytoplasmic, score: 9.97.
   
 0.910
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
 
 0.893
priA
Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.
   
 
 0.855
dnaX
DNA polymerase III, subunit gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
   
 
 0.848
holB
KEGG: bbe:BBR47_00780 2.8e-37 holB; DNA polymerase III delta' subunit K02341; Psort location: Cytoplasmic, score: 7.50.
   
 
 0.846
EFW24144.1
KEGG: acl:ACL_1319 3.3e-50 uracil-DNA glycosylase superfamily protein; Psort location: Cytoplasmic, score: 7.50.
   
   0.727
EFW24612.1
KEGG: ser:SERP1199 2.5e-75 recJ; single-stranded-DNA-specific exonuclease RecJ K07462; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.725
dnaB
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
  
 
 0.657
rpsF
Ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
  
  
 0.639
recO
DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination.
   
 
 0.624
Your Current Organism:
Solobacterium moorei
NCBI taxonomy Id: 706433
Other names: S. moorei F0204, Solobacterium moorei F0204, Solobacterium moorei str. F0204, Solobacterium moorei strain F0204
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