STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lonEndopeptidase La; KEGG: cac:CAC0456 1.6e-174 lonA; ATP-dependent protease (LonA); K01338 ATP-dependent Lon protease; Psort location: Cytoplasmic, score: 9.97. (768 aa)    
Predicted Functional Partners:
EFW25284.1
ATPase, AAA family; KEGG: saa:SAUSA300_0510 1.8e-07 clpC; endopeptidase K03696; Psort location: CytoplasmicMembrane, score: 8.16.
  
 
 0.761
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
   
 
 0.691
grpE
Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...]
  
  
 0.679
groL
Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
  
 0.660
htpG
Chaperone protein HtpG; Molecular chaperone. Has ATPase activity.
  
  
 0.651
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
  
 0.642
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
  
 0.633
nifJ
KEGG: fnu:FN1170 0. pyruvate-flavodoxin oxidoreductase K03737; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.626
EFW24705.1
Putative ATP-dependent chaperone protein ClpB; KEGG: sax:USA300HOU_0933 4.5e-236 clpB; endopeptidase ClpB K03695; Psort location: Cytoplasmic, score: 9.97; Belongs to the ClpA/ClpB family.
  
 
 0.620
EFW24020.1
Trypsin; KEGG: tpd:Teth39_0166 7.6e-67 2-alkenal reductase; Psort location: Cytoplasmic, score: 7.50.
  
 0.614
Your Current Organism:
Solobacterium moorei
NCBI taxonomy Id: 706433
Other names: S. moorei F0204, Solobacterium moorei F0204, Solobacterium moorei str. F0204, Solobacterium moorei strain F0204
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.