node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EFW24604.1 | adk | HMPREF9430_00872 | HMPREF9430_00167 | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.563 |
EFW24604.1 | apt | HMPREF9430_00872 | HMPREF9430_00794 | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.961 |
EFW24604.1 | deoD | HMPREF9430_00872 | HMPREF9430_01306 | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | KEGG: acl:ACL_0698 5.3e-66 deoD; purine-nucleoside phosphorylase K03784; Psort location: Cytoplasmic, score: 9.97. | 0.954 |
EFW24604.1 | guaA | HMPREF9430_00872 | HMPREF9430_01841 | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | 0.730 |
EFW24604.1 | hpt | HMPREF9430_00872 | HMPREF9430_01931 | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | KEGG: lla:L25115 3.1e-54 hpt; hypoxanthine phosphoribosyltransferase K00760; Psort location: Cytoplasmic, score: 9.97; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.966 |
EFW24604.1 | tilS | HMPREF9430_00872 | HMPREF9430_01930 | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. | 0.532 |
EFW24604.1 | xpt | HMPREF9430_00872 | HMPREF9430_02052 | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.961 |
EFW25353.1 | adk | HMPREF9430_00123 | HMPREF9430_00167 | AICARFT/IMPCHase bienzyme; KEGG: bfs:BF2688 5.2e-155 5-aminoimidazole-4-carboxamide ribonucleotide transformylase K01492; Psort location: Cytoplasmic, score: 7.50. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.669 |
EFW25353.1 | apt | HMPREF9430_00123 | HMPREF9430_00794 | AICARFT/IMPCHase bienzyme; KEGG: bfs:BF2688 5.2e-155 5-aminoimidazole-4-carboxamide ribonucleotide transformylase K01492; Psort location: Cytoplasmic, score: 7.50. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.963 |
EFW25353.1 | guaA | HMPREF9430_00123 | HMPREF9430_01841 | AICARFT/IMPCHase bienzyme; KEGG: bfs:BF2688 5.2e-155 5-aminoimidazole-4-carboxamide ribonucleotide transformylase K01492; Psort location: Cytoplasmic, score: 7.50. | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | 0.912 |
EFW25353.1 | hpt | HMPREF9430_00123 | HMPREF9430_01931 | AICARFT/IMPCHase bienzyme; KEGG: bfs:BF2688 5.2e-155 5-aminoimidazole-4-carboxamide ribonucleotide transformylase K01492; Psort location: Cytoplasmic, score: 7.50. | KEGG: lla:L25115 3.1e-54 hpt; hypoxanthine phosphoribosyltransferase K00760; Psort location: Cytoplasmic, score: 9.97; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.935 |
EFW25353.1 | purA | HMPREF9430_00123 | HMPREF9430_01738 | AICARFT/IMPCHase bienzyme; KEGG: bfs:BF2688 5.2e-155 5-aminoimidazole-4-carboxamide ribonucleotide transformylase K01492; Psort location: Cytoplasmic, score: 7.50. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.977 |
EFW25353.1 | tilS | HMPREF9430_00123 | HMPREF9430_01930 | AICARFT/IMPCHase bienzyme; KEGG: bfs:BF2688 5.2e-155 5-aminoimidazole-4-carboxamide ribonucleotide transformylase K01492; Psort location: Cytoplasmic, score: 7.50. | tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. | 0.645 |
EFW25353.1 | xpt | HMPREF9430_00123 | HMPREF9430_02052 | AICARFT/IMPCHase bienzyme; KEGG: bfs:BF2688 5.2e-155 5-aminoimidazole-4-carboxamide ribonucleotide transformylase K01492; Psort location: Cytoplasmic, score: 7.50. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.852 |
adk | EFW24604.1 | HMPREF9430_00167 | HMPREF9430_00872 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.563 |
adk | EFW25353.1 | HMPREF9430_00167 | HMPREF9430_00123 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | AICARFT/IMPCHase bienzyme; KEGG: bfs:BF2688 5.2e-155 5-aminoimidazole-4-carboxamide ribonucleotide transformylase K01492; Psort location: Cytoplasmic, score: 7.50. | 0.669 |
adk | apt | HMPREF9430_00167 | HMPREF9430_00794 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.918 |
adk | guaA | HMPREF9430_00167 | HMPREF9430_01841 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | 0.954 |
adk | hpt | HMPREF9430_00167 | HMPREF9430_01931 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | KEGG: lla:L25115 3.1e-54 hpt; hypoxanthine phosphoribosyltransferase K00760; Psort location: Cytoplasmic, score: 9.97; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.964 |
adk | purA | HMPREF9430_00167 | HMPREF9430_01738 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.636 |