STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFQ04538.1Trypsin. (369 aa)    
Predicted Functional Partners:
EFQ04539.1
Metallo-beta-lactamase domain protein.
  
  
 0.835
rlmH
Putative rRNA large subunit m3Psi methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.
       0.814
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
       0.786
crt
KEGG: cac:CAC2712 3.9e-86 crt; 3-hydroxybutyryl-CoA dehydratase K01715; Psort location: Cytoplasmic, score: 8.96.
    
  0.662
alaS
alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
 
  0.644
EFQ03907.1
HMGL-like protein; KEGG: cdf:CD0797 1.6e-80 putative hydroxymethylglutaryl-CoA lyase; K01640 hydroxymethylglutaryl-CoA lyase; Psort location: Cytoplasmic, score: 8.96.
    
  0.639
EFQ04241.1
Tetratricopeptide repeat protein; KEGG: rle:RL4106 2.6e-11 cya; putative adenylate/guanylate cyclase K01768.
  
 0.611
EFQ05037.1
Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; KEGG: cbk:CLL_A2296 8.8e-192 PTS system, fructose-specific component family; K02768 PTS system, fructose-specific IIA component; K02769 PTS system, fructose-specific IIB component K02770; Psort location: CytoplasmicMembrane, score: 10.00.
    
 
 0.607
EFQ03945.1
Hydrolase, NUDIX family; KEGG: tme:Tmel_0555 3.6e-37 NUDIX hydrolase; K01515 ADP-ribose pyrophosphatase; Psort location: Cytoplasmic, score: 8.96.
    
  0.588
lon
Endopeptidase La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
   
 0.572
Your Current Organism:
Megasphaera micronuciformis
NCBI taxonomy Id: 706434
Other names: M. micronuciformis F0359, Megasphaera micronuciformis F0359, Megasphaera micronuciformis str. F0359, Megasphaera micronuciformis strain F0359
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.