STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFM25018.1Putative low-complexity protein; PFAM: Pentapeptide repeats (8 copies). (179 aa)    
Predicted Functional Partners:
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.593
AFM27887.1
Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; DNA gyrase B; DNA gyrase B subunit, carboxyl terminus.
   
 
 0.593
AFM27737.1
Putative ATPase; PFAM: Protein kinase domain; Response regulator receiver domain; GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; Hpt domain.
 
 
 0.485
AFM28125.1
Putative ATPase; PFAM: Protein kinase domain; GAF domain; Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
 
 
 0.484
AFM24335.1
WD40 repeat-containing protein; PFAM: Protein kinase domain; WD domain, G-beta repeat.
 
  
 0.443
AFM23048.1
PFAM: von Willebrand factor type A domain.
 
     0.434
AFM28061.1
PFAM: Tetratricopeptide repeat.
 
  
 0.400
Your Current Organism:
Desulfomonile tiedjei
NCBI taxonomy Id: 706587
Other names: D. tiedjei DSM 6799, Desulfomonile tiedjei DCB-1, Desulfomonile tiedjei DSM 6799, Desulfomonile tiedjei str. DSM 6799, Desulfomonile tiedjei strain DSM 6799
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