STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFM26683.1Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID; PFAM: PTS system mannose/fructose/sorbose family IID component; manually curated. (253 aa)    
Predicted Functional Partners:
AFM23855.1
Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC; PFAM: PTS system sorbose-specific iic component.
 
 
 0.999
AFM23857.1
Phosphotransferase system, mannose/fructose-specific component IIA; PFAM: PTS system fructose IIA component.
 
 0.999
AFM23856.1
Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB; PFAM: PTS system sorbose subfamily IIB component.
 
 
 0.994
AFM26682.1
PFAM: PTS HPr component phosphorylation site; TIGRFAM: Phosphotransferase System HPr (HPr) Family.
 
  
 0.987
AFM26681.1
Phosphoenolpyruvate--protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
   
 0.917
AFM23974.1
Phosphomannomutase; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, C-terminal domain; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I.
    
 0.905
smpB
SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]
       0.800
AFM28119.1
PFAM: Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2.
 
  
 0.701
AFM27253.1
Glucosamine 6-phosphate synthetase; PFAM: SIS domain; Glutamine amidotransferases class-II; contains amidotransferase and phosphosugar isomerase domains.
  
  
 0.425
lpxC
UDP-3-O-(3-hydroxymyristoyl) N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.
       0.411
Your Current Organism:
Desulfomonile tiedjei
NCBI taxonomy Id: 706587
Other names: D. tiedjei DSM 6799, Desulfomonile tiedjei DCB-1, Desulfomonile tiedjei DSM 6799, Desulfomonile tiedjei str. DSM 6799, Desulfomonile tiedjei strain DSM 6799
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.