STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFM27005.1PFAM: Pyruvate phosphate dikinase, PEP/pyruvate binding domain. (1493 aa)    
Predicted Functional Partners:
AFM27503.1
Pyruvate phosphate dikinase; PFAM: PEP-utilising enzyme, TIM barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate phosphate dikinase, PEP/pyruvate binding domain; TIGRFAM: pyruvate, phosphate dikinase; Belongs to the PEP-utilizing enzyme family.
  
  
 
0.930
AFM26825.1
PFAM: Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain.
  
 
 0.919
ldh
Malate dehydrogenase (NAD); Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
 
 0.916
AFM25041.1
Pyruvate/oxaloacetate carboxyltransferase; PFAM: HMGL-like; Conserved carboxylase domain.
    
 0.915
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
    
 0.915
pdhA
Pyruvate dehydrogenase E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
    
 0.914
AFM26855.1
PFAM: subunit; TIGRFAM: sodium ion-translocating decarboxylase, beta subunit.
  
 
 0.914
AFM23267.1
PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
    
 0.912
AFM24055.1
Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain.
    
 0.912
AFM25220.1
2-oxoacid:ferredoxin oxidoreductase, beta subunit; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain.
    
 0.912
Your Current Organism:
Desulfomonile tiedjei
NCBI taxonomy Id: 706587
Other names: D. tiedjei DSM 6799, Desulfomonile tiedjei DCB-1, Desulfomonile tiedjei DSM 6799, Desulfomonile tiedjei str. DSM 6799, Desulfomonile tiedjei strain DSM 6799
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.