node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
infA | rplD | Desti_2926 | Desti_5263 | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. | 50S ribosomal protein L4, bacterial/organelle; Forms part of the polypeptide exit tunnel. | 0.999 |
infA | rpsB | Desti_2926 | Desti_3972 | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. | PFAM: Ribosomal protein S2; TIGRFAM: ribosomal protein S2, bacterial type; Belongs to the universal ribosomal protein uS2 family. | 0.995 |
infA | rpsE | Desti_2926 | Desti_5279 | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. | SSU ribosomal protein S5P; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. | 0.999 |
infA | rpsF | Desti_2926 | Desti_1254 | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. | SSU ribosomal protein S6P; Binds together with S18 to 16S ribosomal RNA. | 0.978 |
infA | rpsG | Desti_2926 | Desti_5258 | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. | Ribosomal protein S7, bacterial/organelle; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. | 0.999 |
infA | rpsI | Desti_2926 | Desti_0400 | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. | PFAM: Ribosomal protein S9/S16; Belongs to the universal ribosomal protein uS9 family. | 0.971 |
infA | rpsJ | Desti_2926 | Desti_5261 | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. | Ribosomal protein S10, bacterial/organelle; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.998 |
infA | rpsL | Desti_2926 | Desti_5257 | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. | SSU ribosomal protein S12P; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. | 0.999 |
infA | rpsO | Desti_2926 | Desti_4064 | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. | Ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. | 0.996 |
infA | rpsS | Desti_2926 | Desti_5266 | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. | SSU ribosomal protein S19P; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. | 0.999 |
rplD | infA | Desti_5263 | Desti_2926 | 50S ribosomal protein L4, bacterial/organelle; Forms part of the polypeptide exit tunnel. | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. | 0.999 |
rplD | rpsB | Desti_5263 | Desti_3972 | 50S ribosomal protein L4, bacterial/organelle; Forms part of the polypeptide exit tunnel. | PFAM: Ribosomal protein S2; TIGRFAM: ribosomal protein S2, bacterial type; Belongs to the universal ribosomal protein uS2 family. | 0.999 |
rplD | rpsE | Desti_5263 | Desti_5279 | 50S ribosomal protein L4, bacterial/organelle; Forms part of the polypeptide exit tunnel. | SSU ribosomal protein S5P; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. | 0.999 |
rplD | rpsF | Desti_5263 | Desti_1254 | 50S ribosomal protein L4, bacterial/organelle; Forms part of the polypeptide exit tunnel. | SSU ribosomal protein S6P; Binds together with S18 to 16S ribosomal RNA. | 0.995 |
rplD | rpsG | Desti_5263 | Desti_5258 | 50S ribosomal protein L4, bacterial/organelle; Forms part of the polypeptide exit tunnel. | Ribosomal protein S7, bacterial/organelle; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. | 0.999 |
rplD | rpsI | Desti_5263 | Desti_0400 | 50S ribosomal protein L4, bacterial/organelle; Forms part of the polypeptide exit tunnel. | PFAM: Ribosomal protein S9/S16; Belongs to the universal ribosomal protein uS9 family. | 0.997 |
rplD | rpsJ | Desti_5263 | Desti_5261 | 50S ribosomal protein L4, bacterial/organelle; Forms part of the polypeptide exit tunnel. | Ribosomal protein S10, bacterial/organelle; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.999 |
rplD | rpsL | Desti_5263 | Desti_5257 | 50S ribosomal protein L4, bacterial/organelle; Forms part of the polypeptide exit tunnel. | SSU ribosomal protein S12P; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. | 0.999 |
rplD | rpsO | Desti_5263 | Desti_4064 | 50S ribosomal protein L4, bacterial/organelle; Forms part of the polypeptide exit tunnel. | Ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. | 0.998 |
rplD | rpsS | Desti_5263 | Desti_5266 | 50S ribosomal protein L4, bacterial/organelle; Forms part of the polypeptide exit tunnel. | SSU ribosomal protein S19P; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. | 0.999 |