STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SSLN_LOCUS7079Uncharacterized protein. (637 aa)    
Predicted Functional Partners:
SSLN_LOCUS2287
Fanconi anemia group M protein.
   
 0.999
SSLN_LOCUS13
Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
    
 0.940
SSLN_LOCUS3965
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
   
 0.901
SSLN_LOCUS6434
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
  
 0.876
A0A183TBA3
ERCC4 domain-containing protein.
   
 0.865
SSLN_LOCUS9648
Zinc-hook domain-containing protein.
  
 0.854
SSLN_LOCUS9872
DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. Belongs to the RecA family. RAD51 subfamily.
  
 0.849
SSLN_LOCUS4426
RMI1_N domain-containing protein.
    
 0.846
SSLN_LOCUS4428
UBA domain-containing protein.
    
 0.846
A0A3P7EVS8
GIY-YIG domain-containing protein.
    
 0.844
Your Current Organism:
Schistocephalus solidus
NCBI taxonomy Id: 70667
Other names: S. solidus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.