Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SSLN_LOCUS8461Uncharacterized protein. (234 aa)    
Predicted Functional Partners:
SSLN_LOCUS9276
DNA polymerase eta.
  
 
 0.966
SSLN_LOCUS4391
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
  
 
 0.955
A0A183TD65
DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family.
   
 0.955
SSLN_LOCUS2287
Fanconi anemia group M protein.
    
 
 0.944
A0A3P7D502
Uncharacterized protein.
   
 0.902
A0A183TJ23
ENDO3c domain-containing protein.
   
 
 0.896
A0A3P7D9P7
Uncharacterized protein.
   
 0.877
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
  
 
 0.856
A0A183T948
BRCT domain-containing protein.
    
 
 0.841
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
    
 
 0.772
Your Current Organism:
Schistocephalus solidus
NCBI taxonomy Id: 70667
Other names: S. solidus
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.