A0A183TDR9 protein (Schistocephalus solidus)

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second shell of interactors

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

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Score

A0A183TDR9

Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (245 aa)

Predicted Functional Partners:

SSLN_LOCUS687

0.767

A0A183T3T7

0.767

KATNAL2

0.715

SSLN_LOCUS6747

0.705

SSLN_LOCUS5245

0.689

A0A183T6G8

0.677

SSLN_LOCUS6092

0.668

SSLN_LOCUS4081

0.663

SSLN_LOCUS6405

0.663

A0A183TA21

0.663

Your Current Organism:

Schistocephalus solidus

NCBI taxonomy Id: 70667
Other names: S. solidus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A183T3T7	A0A183TA21	A0A183T3T7	A0A183TA21	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	AAA domain-containing protein.	0.663
A0A183T3T7	A0A183TDR9	A0A183T3T7	A0A183TDR9	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	0.767
A0A183T3T7	KATNAL2	A0A183T3T7	A0A3P7BHJ1	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	0.715
A0A183T3T7	SSLN_LOCUS4081	A0A183T3T7	A0A183SIN3	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Vps4_C domain-containing protein.	0.682
A0A183T3T7	SSLN_LOCUS5245	A0A183T3T7	A0A183SLZ7	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Exosome complex component RRP43.	0.410
A0A183T3T7	SSLN_LOCUS6092	A0A183T3T7	A0A0X3Q235	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	0.553
A0A183T3T7	SSLN_LOCUS6405	A0A183T3T7	A0A183SQA7	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	AAA domain-containing protein.	0.682
A0A183T3T7	SSLN_LOCUS6747	A0A183T3T7	A0A183SR99	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Uncharacterized protein.	0.663
A0A183T3T7	SSLN_LOCUS687	A0A183T3T7	A0A183S8Y9	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Uncharacterized protein.	0.663
A0A183T6G8	A0A183TA21	A0A183T6G8	A0A183TA21	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	AAA domain-containing protein.	0.663
A0A183T6G8	A0A183TDR9	A0A183T6G8	A0A183TDR9	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	0.677
A0A183T6G8	KATNAL2	A0A183T6G8	A0A3P7BHJ1	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	0.715
A0A183T6G8	SSLN_LOCUS4081	A0A183T6G8	A0A183SIN3	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Vps4_C domain-containing protein.	0.682
A0A183T6G8	SSLN_LOCUS5245	A0A183T6G8	A0A183SLZ7	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Exosome complex component RRP43.	0.410
A0A183T6G8	SSLN_LOCUS6092	A0A183T6G8	A0A0X3Q235	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	0.553
A0A183T6G8	SSLN_LOCUS6405	A0A183T6G8	A0A183SQA7	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	AAA domain-containing protein.	0.682
A0A183T6G8	SSLN_LOCUS6747	A0A183T6G8	A0A183SR99	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Uncharacterized protein.	0.663
A0A183T6G8	SSLN_LOCUS687	A0A183T6G8	A0A183S8Y9	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Uncharacterized protein.	0.663
A0A183TA21	A0A183T3T7	A0A183TA21	A0A183T3T7	AAA domain-containing protein.	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	0.663
A0A183TA21	A0A183T6G8	A0A183TA21	A0A183T6G8	AAA domain-containing protein.	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	0.663

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Network Stats

number of nodes:

11

number of edges:

13

average node degree:

2.36

avg. local clustering coefficient:

0.885

expected number of edges:

10

PPI enrichment p-value:

0.233

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0046907

Intracellular transport

5 of 521

1.35

0.95

0.0054

GO:0006886

Intracellular protein transport

4 of 319

1.46

0.92

0.0092

GO:0015031

Protein transport

5 of 823

1.15

0.74

0.0124

GO:0006606

Protein import into nucleus

2 of 40

2.06

0.74

0.0427

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0043227

Membrane-bounded organelle

11 of 7441

0.54

0.43

0.0011

GO:0043229

Intracellular organelle

11 of 7650

0.52

0.42

0.0011

GO:0005737

Cytoplasm

10 of 6797

0.53

0.41

0.0031

GO:0043231

Intracellular membrane-bounded organelle

10 of 6999

0.52

0.4

0.0033

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:3521

LAG1, DNA binding, and Protein of unknown function DUF6699

2 of 5

2.97

1.61

0.0012

CL:2008

Mixed, incl. Exportin-1/5, and Zinc finger, RanBP2-type

2 of 5

2.97

1.61

0.0012

CL:1954

Nuclear pore

3 of 32

2.34

1.58

0.0011

CL:15982

Mostly uncharacterized, incl. Serine-type endopeptidase activity, and Multifunctional anion exchangers

3 of 145

1.68

1.17

0.0035

CL:16106

Mixed, incl. Multifunctional anion exchangers, and Tyrosine/serine-protein phosphatase IphP-type

2 of 34

2.14

1.1

0.0085

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-68875

Mitotic Prophase

3 of 53

2.12

1.62

0.00076

MAP-68886

M Phase

4 of 175

1.72

1.47

0.00070

MAP-2980766

Nuclear Envelope Breakdown

2 of 26

2.25

0.92

0.0198

MAP-69278

Cell Cycle, Mitotic

4 of 630

1.17

0.66

0.0253

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR040159

Suppressor of hairless-like

2 of 2

3.37

1.39

0.0032

IPR037095

RBP-J/Cbf11, DNA binding domain superfamily

2 of 2

3.37

1.39

0.0032

IPR036358

Beta-trefoil domain superfamily

2 of 2

3.37

1.39

0.0032

IPR015351

RBP-J/Cbf11/Cbf12, DNA binding

2 of 2

3.37

1.39

0.0032

IPR015350

Beta-trefoil DNA-binding domain

2 of 2

3.37

1.39

0.0032

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM01268

Beta-trefoil DNA-binding domain

2 of 2

3.37

1.93

0.00034

SM01267

LAG1, DNA binding

2 of 2

3.37

1.93

0.00034

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